Tuesday, April 2, 2013

江蘇省衛生廳:尚無針對H7N9禽流感病毒疫苗

週二, 02 四月 2013

中新网4月2日电 江苏省卫生厅日前在其官方网站发布人感染H7N9禽流感疫情答问。答问指出,目前国内外尚无针对H7N9禽流感病毒的疫苗。以下是答问全文:
  一、 此次人感染H7N9禽流感的患者从何种途径感染?有无密切接触者发病或死亡?密切接触者是否受到医学观察?
  答:此次人感染的H7N9流感病毒从病毒生物学上属于禽源流感病毒,既往国际上所发现的人感染H7亚型的流感病毒也多来自于禽类,但截至目前,3例确诊患者的具体感染来源尚不清楚。
  根据我国不明原因肺炎管理的有关规定,上海、安徽和江苏(安徽的1例患者在江苏南京救治)的卫生部门对患者的所有密切接触者都实施了医学观察。上海的1例确诊患者发病前,其2名家庭成员也发生了重症肺炎,病因仍在调查和检测中。该家庭的3例患者的发病是否存在关联,有待进一步调查。除此以外,上海、安徽确诊患者的所有密切接触者目前均未发现类似病例。

  二、 目前国家卫生和计划生育委员会以及各地卫生部门采取了哪些措施?开展了哪些调查工作?
  病例出现后,当地卫生部门高度重视,及时采取了临床救治、流行病学调查、标本采集与送检、密切接触者医学观察等,并加强了对不明原因肺炎病例的监测工作。
  国家卫生和计划生育委员会对此次疫情高度重视,接到重症不明原因肺炎疫情报告后,立即向上海、安徽和江苏派出专家工作组,指导当地开展患者的救治和调查工作,召开多部门会商会,对疫情性质进行分析研判,并安排部署了相关调查、防控和应对准备工作。中国疾控中心接到病例报告和送检标本后,及时开展了疫情风险研判和实验室检测研究,明确了相关病原学诊断。
  三、上海的两例确诊患者均于3月上旬死亡,为什么国家卫生和计划生育委员会3月31日才公布疫情?
  答:此次人感染的H7N9禽流感病毒,是全球首次发现的新亚型流感病毒,尚未纳入我国法定报告传染病监测报告系统。
  上海市医疗卫生机构发现上述病例时,及时开展了相关实验室筛查,先后排除了感染季节性H1N1和H3N2流感、甲型H1N1流感、人感染高致病性禽流感(H5N1)以及非典、新型冠状病毒的可能。在进一步检测中,上海市公共卫生临床中心于3月22日发现患者可能感染H7流感,之后将相关标本送中国疾病预防控制中心。3月29日下午,中国疾病预防控制中心从送检的病例标本中分离到3株H7N9禽流感病毒。国家卫生和计划生育委员会组织专家进一步核实,根据实验室检测结果,并结合患者的临床表现、流行病学资料等进行综合分析,判定上述患者为人感染H7N9禽流感病毒病例。国家卫生和计划生育委员会依法于3月31日向社会公布。
  四、此前有媒体报道上海出现一家三口感染不明原因肺炎,其中两人抢救无效死亡,是否与此次报告病例相关?
  2月20-25日,上海市某医院先后收治了患重症肺炎的李姓父子3人,2人经抢救无效死亡。李姓父亲被确诊为H7N9禽流感病毒感染,另2位患者的诊断正在进行中。
  五、H7N9病毒与既往H1N1、H5N1和其他季节性流感病例相比其毒力和传染性如何?
  由于目前只发现3例人感染H7N9禽流感病毒确诊病例,对该病毒及其所致疾病的研究资料十分有限,专家正在对该病毒的毒力和人际传播的能力做进一步判断。
  六、若感染者出现早期症状就及时就医是否可以得到有效治疗?
  基因序列分析显示,该病毒对神经氨酸酶抑制剂类抗流感病毒药物敏感。根据其他型别流感抗病毒治疗的经验,发病后早期使用神经氨酸酶抑制剂类抗流感病毒药物可能是有效的,但对人类新发现的H7N9禽流感病毒感染的特异性治疗手段仍需观察研究。
  七、如何预防H7N9禽流感?是否还有其他特别需要注意的事项?
  流感是一种急性呼吸道感染性疾病。勤洗手、室内勤通风换气、注意营养、保持良好体质有利于预防流感等呼吸道传染病。出现打喷嚏、咳嗽等呼吸道感染症状时,要用纸巾、手帕掩盖口鼻,预防感染他人。此外,还要特别注意尽量避免直接接触病死禽、畜。
  由于医务人员比普通公众接触患有感染性疾病病人的机会更多,建议医务人员在诊治病人过程中采取必要的防护措施。在接诊疑似或确诊H7N9禽流感病例时,应采取有效的防护措施,即标准预防、飞沫传播预防和接触传播预防措施。
  目前国内外尚无针对H7N9禽流感病毒的疫苗。

Hong Kong: Four human cases of Influenza A (#H7N9) in Jiangsu verified by NHFPC

Hong Kong (HKSAR) - The Centre for Health Protection (CHP) of the Department of Health (DH) tonight (April 2) verified with the National Health and Family Planning Commission (NHFPC) four confirmed human cases of Influenza A (H7N9) in Jiangsu, involving one man and three women, aged between 32 and 83, all of whom currently in critical condition.

Laboratory tests on the patients' specimens by the Mainland health authorities yielded positive results for H7N9.

According to the Health Department of Jiangsu, the 45-year-old female patient is a poultry worker and no epidemiological links were identified among the four cases at this stage. So far, the 167 close contacts of the four patients are asymptomatic.

A spokesman for DH stressed that the CHP is closely monitoring the situation, will continue to maintain close liaison with the Mainland health authorities for more case information as well as keep a close eye on the advice from the World Health Organization.

The spokesman also advised travellers especially those returning from Shanghai, Anhui and Jiangsu with respiratory symptoms to wear facial masks and seek medical attention and reveal their travel histories to doctors.

Health-care professionals should also pay special attention to those travellers who might have contact with birds or poultry in the three places.

Members of the public are reminded to take heed of the following preventive advice against avian influenza:

Continued: 
Source: HKSAR Government

Nature Blog: First human deaths from #H7N9 bird flu

| Posted by Rosie Mestel

Posted on behalf of David Cyranoski:
Two men died after being infected with a type of bird flu never before been seen in humans, China reported on March 31. The two Shanghai men, 87 and 27 years old, contracted the H7N9 virus in February and died within 8 days. A 35-year-old woman from Anhui province, who contracted it in March, is now in critical condition.
The path of transmission of the three cases is not clear. The younger woman reportedly had contact with birds, and the 27-year-old man and younger woman were both butchers. After examining 88 close contacts with the infected, China’s CDC has concluded that the virus is not passing between humans.
But two sons of one of those confirmed to have an H7N9 infection also suffered acute pneumonia, and one died. The cause is yet unknown, but health authorities are calling the cluster of severe pneumonia worrisome.
Another case — of a 45-year-old woman in Jiangsu, which lies between Anhui and Shanghai, has been reported but not yet confirmed.
Nature will post more on the news later today.

 
http://blogs.nature.com/news/2013/04/first-human-deaths-from-h7n9-bird-flu.html 

#H7N9 Case List & Map (Updated)

Summary:
Total Confirmed Cases: 7
Total Unconfirmed: 2
Total Confirmed Deaths: 2
Total Unconfirmed Deaths: 2
Total Critical Condition: 5
Days from Onset to Critical: approx. 10

This is a map of Jiangsu Province, and the 4 cases reported today. Click on the map to enlarge.
Jiangsu Province Cases


H7N9 Human Cases 2013

Date of Report:  3/8/13
Name:  Li Family – Father & 2 Sons
Ages: 
55(M)  Son of 87(M)
Adm:  yes
Confirmation:  no
DOD:  2/28

69(M) Eldest son of 87(M)
Adm:  yes
Confirmation:  no
Note:  Recovered and discharged.


Date of Report 3/31/13
Name:  Lee 87(M) Father of 2 above
From:  Shanghai
Adm:  2/24 (?)Shanghai No. 5 People’s Hospital
Onset:  2/19
Notes: No mutual infections among the 3 cases.  88 contacts are fine.  H7N9 has never been contracted to humans before.  Virus shows no signs of being highly contagious.  All sym’s were fever, cough developing into severe pneumonia & difficulty breathing in later stage.
Confirmation:  3/30/13
DOD:  3/4


Date of Report:  3/31/13
Name:  Wu 27(M)
From:  Shanghai
Onset:  2/27
Notes: Sold pork in local market.  No mutual infections among the 3 cases.  88 contacts are fine.  H7N9 has never been contracted to humans before.  Virus shows no signs of being highly contagious.  All sym’s were fever, cough developing into severe pneumonia & difficulty breathing in later stage.
Confirmation:  3/30/13
DOD:  3/10



Date of Report:  3/31/13
Name:  Mr. Han 35(F)
From:  Chuzhou City, Anhui Province
Onset:  3/9
Adm:  Nanjing Hospital, Jiangsu
Notes:  Critical Condition 3/31.  Contact with birds.  No mutual infections among the 3 cases.  88 contacts are fine.  H7N9 has never been contracted to humans before.  Virus shows no signs of being highly contagious.  All sym’s were fever, cough developing into severe pneumonia & difficulty breathing in later stage.
Confirmation:  3/30/13

Date of Report:  4/2/13
Name:  Xu - 45(F)
From:  Jiangning District, Jiangsu Province
Onset:  3/19, dizzy, fever, aches, fatigue
Adm:  3/27, ICU Nanjing
Confirmed:  3/30 – Prov. Ctr for Disease Detection
Confirmed:  4/2 – China CDC
Notes:  Critical Condition.  49 contacts being monitored.  Worked as poultry butcher.

Date of Report:  4/2/13
Name:  Female (48)
From:  Suqian Shuyang, Jiangsu Province
Onset:  3/19, fever, dizzy, cough
Adm:  3/30, Nanjing Hospital ICU
Confirmed:  3/30 Jiangsu Provinial Ctr for Dis. Detection
Confirmed:  4/2  China CDC
Notes:  Critical Condition.  60 contacts monitored.

Date of Report:  4/2/13
Name:  Shen  83(M)
From:  Suzhou Wujiang District, Jiangsu Province
Onset:  3/20, fever, cough, sputum production
Adm:  3/29 Wujiang
Confirmed:  4/1 Jiangsu Provincial Ctr for Disease Detection
Notes:  Critical Condition.  15 contacts monitored.




Date of Report:  4/2/13
Name:  Zhang  32(F)
From:  Wuxi City, unemployed
Onset:  3/21
Adm:  3/28 Wuxi ICU
Confirmed:  3/31 Jiangsu Prov. Ctr for Dis. Detection
Confirmed:  4/2 – China CDC
Notes:  Critical Condition.  43 contact monitored.

#H7N9: Jiangsu Province Confirmed 4 Cases, all in Critical Condition -

2013-04-02

Health Department of Jiangsu Province, Nanjing, BEIJING, April 2 (Reporter ZHU Xiao-ying)

Bulletin, April 2, Jiangsu Province, diagnosed four cases of human infection with the H7N9 avian influenza. Patients Xu, female, 45 years old, Jiangning District, engaged in live poultry slaughter. March 19, fever, dizziness, body aches, fatigue and other symptoms. In the morning of March 27, go to Nanjing sicker ICU treatment in a hospital. Currently, patients in critical condition, is to rescue. On the afternoon of March 30, the Jiangsu Provincial Center for Disease testing positive for H7N9 avian influenza virus nucleic acid. In the afternoon of April 2, review by China CDC influenza center laboratory for the H7N9 avian influenza virus nucleic acid positive.

In accordance with the relevant requirements, the afternoon of April 2, the provincial Health Department organized experts, according to the clinical manifestations, laboratory testing and epidemiological findings, the diagnosis of the cases human infection confirmed cases of the H7N9 avian flu. The patients for the province's first cases of infection with the H7N9 avian flu.

After investigation, the close contacts of the cases of 49 people. Medical observation, so far, all close contacts of the cases were not found to have a fever or respiratory symptoms.

Patients with a mulberry, female, 48 years old, Suqian Shuyang engaged in sheet metal processing. March 19, fever, dizziness, coughing and other symptoms. March 30, sicker patients transferred to a Nanjing hospital ICU treatment. Currently, patients in critical condition, is to rescue. On March 30, the Jiangsu Provincial Center for Disease Detection H7N9 avian influenza virus nucleic acid weakly positive. In the afternoon of April 2, review by China CDC influenza center laboratory for the H7N9 avian influenza virus nucleic acid positive.

In accordance with the relevant requirements, the afternoon of April 2, the provincial Health Department organized experts, according to the clinical manifestations, laboratory testing and epidemiological findings, the diagnosis of the cases human infection confirmed cases of the H7N9 avian flu. After investigation, the close contacts of the cases of a total of 60 people. Medical observation, until now, were not found to have a fever or respiratory symptoms.

Patients Shen, male, 83 years old, Suzhou Wujiang District. March 20 fever, cough, sputum production, accompanied by symptoms such as chest tightness, shortness of breath and chest pain. March 29, sicker patients, treatment to a hospital in Wujiang. Currently, patients in critical condition, is to rescue. On April 1, the Jiangsu Provincial Center for Disease Detection identified as the H7N9 avian influenza virus nucleic acid positive. In accordance with the relevant requirements, the afternoon of April 2, the provincial Health Department organized experts, according to the clinical manifestations, laboratory testing and epidemiological findings, the diagnosis of the cases human infection confirmed cases of the H7N9 avian flu. After investigation, the close contacts of the cases of a total of 15 people. Medical observation, until now, were not found to have a fever or respiratory symptoms.

Patients Zhang, female, 32 years old, Changzhou, now lives in Wuxi city, unemployed. March 21, fever, cough, and other symptoms. On March 28, the sicker patients transferred to a hospital in Wuxi ICU treatment. Currently, patients in critical condition, is to rescue. March 31, identified as the H7N9 avian influenza virus nucleic acid positive by the Jiangsu Provincial Center for Disease Detection. In accordance with the relevant requirements, the afternoon of April 2, the provincial Health Department organized experts, according to the clinical manifestations, laboratory testing and epidemiological findings, the diagnosis of the cases human infection confirmed cases of the H7N9 avian flu. After investigation, the close contacts of the cases of a total of 43 people. Medical observation, until now, were not found to have a fever or respiratory symptoms.

 After the outbreak, the provincial government attaches great importance to the health sector in accordance with the relevant plans and programs to rapidly launch epidemic prevention and control work.

First, the Provincial Health Department established human infection with the H7N9 avian flu prevention and control work leading group, and people infected with the H7N9 bird flu prevention and control of the Group of Experts, medical treatment expert group issued "effectively strengthen human infection with the H7N9 avian flu prevention and control work urgent notice "to strengthen epidemic prevention and control, and to treat the patient.

The specified 16 tertiary hospitals as a province first admitted to the hospital to make every effort, in accordance with the principle of "concentrated heavy suffering, a pool of experts, pooling of resources, centralized treatment, medical treatment, efforts to reduce the mortality.

Third, the development of Jiangsu Province, people infected with H7N9 avian influenza monitoring the investigation and management solutions, organization of medical and health institutions at all levels to strengthen the monitoring of the unexplained cases of pneumonia and influenza-like illness, active search, and strive to early discovery, early reporting, early diagnosis, early isolation and early treatment.

The fourth is to strengthen the hospital infection control hospital infection prevention and control, strict implementation of disinfection and isolation system and norms, strict precautions against the spread of the epidemic hospital.

The fifth is to strengthen the communication links with the departments of agriculture, industry and commerce, business and work together to epidemic prevention and control work. Currently, no epidemiological association exists between the above four cases. The experts have warned that the face of human infection with the H7N9 avian flu, Mo panic, to be alert to.

First, to maintain good personal hygiene, such as washing hands frequently, indoor Qin ventilation. The second is to pay attention to improve nutrition, enhance personal physical. The third is to avoid contact and edible disease (dead), poultry, livestock. The event of fever, cough and other symptoms of acute respiratory infections, especially high fever, breathing difficulties, you should seek immediate medical attention. Jiangsu Provincial Health Department will continue to make every effort to epidemic prevention and control work, and take effective measures to effectively protect public health. (End)

#H7N9: China steps up H7N9 bird flu alert amid rumors

from the Bangkok Post:

Published: 2 Apr 2013
Health authorities ordered medical staff to strengthen monitoring and prepare isolation units for possible new infections with H7N9 avian influenza on Tuesday, amid rumours that doctors had already found more cases in eastern China.

The Beijing city health bureau said it had added H7N9 to its watch-list of viral infections and had received reagent samples for testing patients after the virus, previously unreported in humans, killed at least two people in Shanghai.

The bureau asked hospitals in Beijing to prepare for emergencies and stockpile adequate medical supplies, adding that no infections were reported among the city's 20 million people by Tuesday.

Similar measures were reportedly ordered in Shanghai and other major cities, as well as in Hong Kong and Taiwan.

An unconfirmed hospital report posted on the popular, Twitter-like microblogging website Weibo said health experts in the eastern city of Nanjing, close to Shanghai, gave "preliminary confirmation" of H7N9 in a 45-year-old woman who worked as a poultry butcher.
The user of the microblog posted a photograph of the hospital report and was listed as an "administrative director" of a hospital in Nanjing.

Concern was also raised after two sons of an 87-year-old Shanghai man who died of H7N9 were both treated for severe pneumonia, from which one of them died.
The government has so far reported only three confirmed infections.

http://www.bangkokpost.com/breakingnews/343573/china-steps-up-h7n9-bird-flu-alert-amid-rumours-of-more-cases

Hong Kong: Sec for Food & Health (SFH) on human cases of Influenza A (#H7N9) on the Mainland

April 2, 2013

Hong Kong (HKSAR) - Following is the transcript of remarks made by the Secretary for Food and Health, Dr Ko Wing-man, after officiating at a public function this afternoon (April 2):

Reporter: (On the outbreak of human cases of Influenza A (H7N9) on the Mainland.)

Secretary for Food and Health: In themorning of March 31, we received notification (from the National Health and Family Planning Commission) of three cases of Influenza A (H7N9) affecting three persons in Shanghai and Anhui in the Mainland. The two patients in Shanghai have passed away and the other patient in Anhui is still receiving intensive medical treatment in Nanjing. We are concerned about these reports because, firstly, two of the three patients have already died and hence superficially the death rate is quite high.

Secondly, there is no epidemiological linkage among the three reported cases which means that the three patients might have contracted the illness through different sources. This will have an implication as to whether there is a spreading of this new H7N9 virus among poultry in the Mainland.

Reporter: (On the enhanced surveillance and control measures in Hong Kong.)

Secretary for Food and Health: I convened an urgent meeting this morning with the Centre for Health Protection (of the Department of Health), the Hospital Authority, the Centre for Food Safety (of the Food and Environmental Hygiene Department), and the Agriculture, Fisheries and Conservation Department (to discuss the enhanced surveillance and control measures in view of the confirmed human cases of Influenza A (H7N9) on the Mainland.) Various measures will be stepped up. Regarding the border control, we will ensure that the temperature measuring arrangement at all entry points to Hong Kong will be strictly adhered to.

The infectious control measures in the hospitals will also be stepped up.

Reporter: What do we know of this new virus so far?

Secretary for Food and Health: The Mainland Authority has already uploaded the full gene sequence of this particular H7N9 virus onto the website and our experts in virology are able to have some insights into the properties of the virus. Firstly, it has an element enabling it to be adapted to the human environment and that is why there are human infections. Secondly and luckily, there is no evidence to show that there is drug-resistance (of this virus) to the two commonly used anti-influenza medications, including Tamiflu.

(Please also refer to the Chinese portion of the transcript.)
Source: HKSAR Government
http://7thspace.com/headlines/435241/sfh_on_human_cases_of_influenza_a_h7n9_on_the_mainland.html

Hong Kong: Visitors To Clinical Areas of Public Hospitals & Clinics Will Also Be Advised to Wear Surgical Mask #H7N9

April 2, 2013
Hong Kong (HKSAR) - Representatives from the Department of Health (DH) and the Hospital Authority (HA) met today (April 2) to discuss the updated situation of the confirmed human cases of Influenza A (H7N9) in the Mainland and will work together in enhancing the surveillance and control measures for the disease.

Speaking at a media session after the meeting, the Controller of the Centre for Health Protection (CHP) of the DH, Dr Leung Ting-hung, expressed concern on the latest development of the disease in the Mainland.

"The mortality of Influenza A (H7N9) is very high.

Although there is no evidence to show human-to-human transmission, the mutation potential of the virus is high. As such, we will not treat the disease lightly,"
Dr Leung said.

"Doctors are advised to be vigilant and report any suspected cases to the CHP. Health-care workers should exercise appropriate infection control measures at all times.

The public should pay particular attention to personal and environmental hygiene and avoid direct contact with animals, birds or poultry,"
he said, adding that the Alert Response Level under the Government's Preparedness Plan for Influenza Pandemic 2012 is activated and that relevant surveillance and control measures have been enhanced.

Dr Leung also advised travellers especially those returning from Shanghai and Anhui with respiratory symptoms to wear facial masks and seek medical attention and reveal their travel histories to doctors. Health-care professionals should also pay special attention to those travellers who might have contact with birds or poultry in the two places.

The CHP will closely monitor the situation, continue to maintain close liaison with the Mainland health authorities and keep a close eye on the advice from the World Health Organization.



Also speaking at the media session, the Chief Infection Control Officer of the HA, Dr Dominic Tsang, stressed that while working closely with the CHP, the HA has enhanced surveillance for patients with influenza symptoms. The frontline health-care staff of accident and emergency departments will pay special attention to those patients referred by the Port Health Office under the DH, while hospital laboratories will provide full support for timely test services. Visitors to the clinical areas of the public hospitals and clinics will also be advised to wear surgical mask.

Continued
Source: HKSAR Government

Hong Kong Sec. Food & Hlth Bureau: Preliminary Analysis Giral Gene Map H7N9 Comes From Birds, Not Tamiflu Resistant

Translation out of China
Excerpt:
BEIJING, April 2, according to the Hong Kong electronic media news, Ko Wing-man, the Secretary of the Hong Kong Food and Health Bureau said that the H7N9 avian flu cases in the Mainland, the experts had preliminary analysis of viral gene map that birds "shuffle" and appear, but not yet occurred in two drugs Tamiflu resistance.
Ko Wing-man said, after the morning meeting with Government departments and relevant experts, the H7N9 virus map, still think the virus from birds, nor are resistant, but we have heard that two relatives of the patients also died of pneumonia, not yet grasp whether they are infected, will come back to the mainland authorities to understand.

#H7N9: Anhui Case Bought Chicken @ Farmers Market Week Before Onset

Anhui H7N9 avian flu before the onset of the farmers market to buy chicken

Translation out of China -- 2013-04-02

Has been diagnosed of human infection with the H7N9 avian flu cases in the 87-year-old Lee and 27-year-old Wu by actively died in Nanjing, Jiangsu, Anhui, Mr. Han treatment.
The reporters visited three of the patient's disease process and more details. Lee, 87-year-old did not come into contact with poultry, and also do not have to go out history. 27-year-old Wu in the vegetable market sales of pork, no contact with poultry. Mr. Han had bought a chicken at the farmers market the week before onset.

Taiwan: Jiang Yi Hua: ready to start the defense system of the avian flu

April 2, 2013
(CNA reporter Zeng Ying Yu Taipei 2, 2009) of the Executive Yuan Jiang Yi Hua said today, the Chinese mainland outbreak of human infection with the H7N9 avian influenza, based on the prevention of avian influenza and SARS experience in the past, and ready to start the defense systems.
Afternoon in the Legislative Yuan, the Chinese KMT Legislator Lee Ching-hua said that the outbreak of human infection with the H7N9 strain of bird flu cases in mainland China, Executive Yuan, how to respond? Frequent cross-strait exchanges, whether to strengthen border management?
Jiang Yi Hua said answering a question, start to appear more cases, not only in Taiwan, the full World Health Organization will be kept strictly preparedness. The Executive Yuan will guard against avian flu and SARS (Severe Acute Respiratory Syndrome) based on past experience, "probably to be ready to start the defense system".
The border management part, he said, as long as detected by the temperature detection or otherwise, will be done, but the fear is newly infected with no fever or other symptoms, would be more tricky.
Jiang Yi Hua said he never heard of farms in Taiwan have similar cases, but is OK in the end there is no precedent, will ask the Department of Health and the Council of Agriculture report explicitly; migratory birds have monitoring mechanisms, with two days before the Chinese mainland outbreak, the COA has already started to rise level.

#Coronavirus: Health Authority: There are Corona virus in Abu Dhabi

Arabic Translation
4/1/13
Confirmed the Health Authority in Abu Dhabi it is coordinating with the Ministry of Health and health authorities and the concerned authorities in the country to monitor the virus, "Corona."
She has taken the necessary measures and precautions and in accordance with the recommendations of scientific and conditions and standards of the World Health Organization, stressing that there is no case currently installed within the emirate.
The Commission pointed out that if the suspect in any case meet the conditions necessary examination available in the Emirate of Abu Dhabi and specifically in the hospital Sheikh Khalifa Medical City.
She issued a circular in December 2012 for all health providers in the emirate on coping mechanisms and reporting in the event of suspected HIV infection Taji new virus (Corona) and asked all health facilities to follow the method of dealing with the situation of suspected virus coronary accordance with instructions and standards body and prompt reporting electronically any case fall within the definition of the condition the new infected.
And necessitated body at all health facilities to inform the operations center in the cases that are entered intensive care and to which it applies describe the situation of the virus coronary new, as requested by the Commission of all health facilities into account procedures to prevent infection and control of epidemic diseases with symptoms of acute respiratory.



Guoguang: Taiwan has the ability to manufacture the H7N9 vaccine

4/2/13
Translation out of China
WASHINGTON, April 2 reported (Central News Agency reporter Luo Xiuwen Taipei Xinhua) China has recently made the H7N9 avian flu, there are two people died. Chairman of ADImmune, Zhan Qixian Guoguang with the production of the H1N1 vaccine technology can be taken when necessary analog production model (mockup), H7N9 vaccine production.
Zhan Qixian H7N9 is a new strain of the virus, there is no vaccine, H7N9 and H1N1 "brothers and sisters" in case of the outbreak of the pandemic H1N1 vaccine production can simulate emergency production of vaccines; since a single virus, 2 months to produce 5000000-10000000.

Monday, April 1, 2013

Beijing will H7N9 initially identified using Tamiflu treatment included in the surveillance of communicable diseases

April 2, 2013 Translation out of China:

Yesterday, the reporter from the Beijing CDC was informed, Shanghai and Anhui report of H7N9 avian flu deaths, Beijing has started the deployment of prevention and control of the city's medical institutions in the H7N9 virus in the city of influenza and pneumonia of unknown causes two large monitoring system at the same time, requires hospital to strengthen emergency duty and reserve-related outbreaks supplies, the need for timely reporting suspicious cases.
Beijing will H7N9 initially identified using Tamiflu treatment included in the surveillance of communicable diseases

City CDC official said the deployment would be for the city to strengthen the prevention and control of H7N9 virus yesterday, the health sector has been convened today, the city's various medical institutions at all levels should strengthen the investigation of suspected cases of unexplained, especially of unexplained pneumonia monitoring suspicious cases, you need the first time to report to the county disease control departments, and at the same time reported to the the unexplained pneumonia monitoring system. With the start of the deployment, H7N9 viruses have been formally incorporated into the city of influenza and pneumonia of unknown causes two major monitoring system, received a suspicious case reports, disease control departments in the shortest time arrived on the scene, and the sample sent to the laboratory detection.
  Before the onset of the H7N9 detection reagents, suspected cases of H7N9 samples will be sent to the Chinese Center for Disease Control to confirm the detection. China CDC is currently sampling blood collection and secretions of confirmed cases of H7N9 virus isolation, while conducting gene sequencing, produced according to the characteristics of the virus detection reagents, detection reagents is determined, in the short The short within hours to determine whether the suspected cases of H7N9 infection.
-snip-
In the prevention and control plan of the city, in the event of suspected cases, on the one hand, county disease control staff will be the first time rushed to the scene of patients attending hospital series of samples, epidemiological investigation and control measures deployment On the other hand, will be released by the Ministry of Health said that the H7N9 virus is sensitive to Tamiflu, initially identified for the use of the Tamiflu antiviral therapy), looking for their close contacts, and for a certain period of time in the timely treatment of suspected cases ( isolated observation, sure its not infected before desegregation.
-snip-
According to the Shanghai Municipal Center for Disease Control survey, the Shanghai patients surnamed Li & Sons 3 basic no history of exposure to live poultry also do not have to go out history, is a retiree living in the district. In addition, an infected 27-year-old Wu is engaged in pork sales in January this year to the Shanghai Minhang one vegetable market from Jiangsu. Although the vegetable market poultry sales, but Wu did not directly come into contact with Wu booth from the poultry stalls at least 20 meters. According to family members of Wu, Wu rarely to the poultry stalls in contact with poultry. But the hospital found that liver function tests Wu Wu have three positive liver function abnormalities.
  In accordance with the requirements of the Department of Agriculture and Veterinary Bureau and the Shanghai Municipal Agricultural Commission, the Shanghai Animal CDC yesterday of recent salvaged upper reaches of the Huangpu River, floating dead pig sampling 34 retained samples for the detection of avian influenza universal primers, avian flu is not found virus.
-snip-




#H7N9: Cluster

This is my case list, and from the articles posted here at this blog, we have a cluster.

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H7N9 Human Cases 2013

Date of Report:  3/8/13
Name:  Li Family – Father & 2 Sons
Ages: 
55(M)  Son of 87(M)
Adm:  yes
Confirmation:  no
DOD:  2/28

69(M) Eldest son of 87(M)
Adm:  yes
Confirmation:  no
Note:  Recovered and discharged.


Date of Report 3/31/13
Name:  Lee 87(M) Father of 2 above
From:  Shanghai
Adm:  2/24 (?)Shanghai No. 5 People’s Hospital
Onset:  2/19
Notes: No mutual infections among the 3 cases.  88 contacts are fine.  H7N9 has never been contracted to humans before.  Virus shows no signs of being highly contagious.  All sym’s were fever, cough developing into severe pneumonia & difficulty breathing in later stage.
Confirmation:  3/30/13
DOD:  3/4


Date of Report:  3/31/13
Name:  Wu 27(M)
From:  Shanghai
Onset:  2/27
Notes: Sold pork in local market.  No mutual infections among the 3 cases.  88 contacts are fine.  H7N9 has never been contracted to humans before.  Virus shows no signs of being highly contagious.  All sym’s were fever, cough developing into severe pneumonia & difficulty breathing in later stage.
Confirmation:  3/30/13
DOD:  3/10



Date of Report:  3/31/13
Name:  Mr. Han 35(F)
From:  Chuzhou City, Anhui Province
Onset:  3/9
Adm:  Nanjing Hospital, Jiangsu
Notes:  Critical Condition 3/31.  Contact with birds.  No mutual infections among the 3 cases.  88 contacts are fine.  H7N9 has never been contracted to humans before.  Virus shows no signs of being highly contagious.  All sym’s were fever, cough developing into severe pneumonia & difficulty breathing in later stage.
Confirmation:  3/30/13

Date of Report:  4/1/13
Name:  24yo
From:  Shanghai
DOD:  yes

WHO: H7N9 avian influenza human infections in China

On 31 March 2013, the China Health and Family Planning Commission notified the World Health Organization (WHO) of three cases of human infection with influenza A(H7N9). The cases were laboratory confirmed on 29 March by China CDC. Laboratory testing for influenza A(H3N2), A (H1N1)pdm09 and A(H5N1), as well as for novel coronavirus, has been negative.
The cases were reported from Shanghai (2 cases) and Anhui province (1 case). All three cases presented with respiratory tract infection with progression to severe pneumonia and breathing difficulties. Disease onset was between 19 February and 15 March 2013. Two of the cases died. The third case is currently in critical condition.
To date no epidemiological link between the cases has been identified. An investigation including follow-up of contacts is ongoing. So far no further cases have been identified among the 88 identified contacts under follow up.
Investigations into the source of infection and mode of transmission are ongoing.
The Chinese government is actively investigating this event and has instituted enhanced surveillance, laboratory strengthening and training of health care professionals for detection, reporting and treatment.
WHO is in contact with the national authorities and is following the event closely. It will issue updates as new information becomes available.

http://www.who.int/csr/don/2013_04_01/en/index.html 

Hong Kong: Stringent surveillance on imported poultry and meat in place to safeguard public health

4/1/13
Hong Kong (HKSAR) - In view of the three confirmed human cases of influenza A (H7N9) in the Mainland, the Centre for Food Safety (CFS) of the Food and Environmental Hygiene Department will closely liaise with the Mainland authorities over any abnormal situation concerning farms supplying chickens and pigs to Hong Kong, and take appropriate actions whenever necessary to protect public health, a CFS spokesman said today (April 1).

The CFS spokesman said, "All live chickens and pigs, and chilled and frozen poultry/meat imported from the Mainland must come from farms and poultry/meat processing plants registered with the inspection and quarantine authorities and to be accompanied with animal health certificates issued by the Mainland authorities concerned.

"CFS officers will be deployed to inspect those registered farms and poultry/meat processing plants to ensure their management complies with the relevant hygienic requirements. Each consignment will be released only after the poultry/meat has been inspected and relevant health certificates verified at the Man Kam To Food Control Office.

"On each consignment of live chickens, the CFS will conduct random tests for avian influenza while live pigs have to go through ante-mortem and post-mortem inspections in slaughterhouses. Only pigs that pass the inspections will be supplied to the market and sold for consumption," he said.

The spokesman said, under the Imported Game, Meat and Poultry Regulations (Cap.

132AK), those who import game, meat or poultry without health certificates commit an offence and are liable to a maximum fine of $50,000 and six months' imprisonment.

"The CFS will closely keep in view of the latest development. Depending on further information about the infection channels in the cases to be established by the health authorities concerned, detail arrangements of appropriate actions and measures will be formulated," the spokesman added.


Source: HKSAR Government

Illegal dead pig trade put pork on Shanghai tables for years

By Xu Chi  |   2013-4-2
PIGS which died from disease or for other reasons were sent to Shanghai markets and restaurants over the past few years because farmers in a neighboring province were reluctant to pay for their proper disposal.

"You Shanghai residents just don't realize how many dead pigs you have eaten before," Xinhua news agency quoted a restaurant owner in Jiaxing as saying.

"In the past years, dead pigs were transported to Shanghai via mini-vans," the owner said.

"A van can carry seven to eight dead pigs and it was very easy to avoid supervision simply by installing wooden layers in the vans. Even if the van was caught by supervisors on the route, the driver would escape by leaving the van and all the pigs behind."

It was not until November last year, when 17 people in Jiaxing were punished for illegally trading in dead pigs that the business started to dry up or go underground, Xinhua said.

Pig farmers in the Zhejiang Province city said they had to pay 50 yuan (US$8) per carcass to "dead pig collectors" hired by the local government to ensure they were disposed of in an eco-friendly way.

An alternative was selling the pigs to illegal traders, who would pay about a yuan per 500 grams, farmers told Xinhua.

Others said they would simply leave the dead pigs by the roadside and the next morning they would be gone, probably taken away by illegal traders.

Official pig collector

Lu Gensong, an official dead pig collector hired by the local government, said he was paid 1,500 yuan a month for the job. It was a task made particularly easy from 2009 to 2012, when he said he didn't collect a single dead pig.

The illegal business hit the headlines last year when three people were sentenced to life in prison for processing more than 77,000 dead pigs and selling them for a total of 8.65 million yuan between January, 2009 and November, 2011. Another 14 people involved were fined or jailed.

That put paid to much of the trade but some farmers still dumped pigs by the roadside to be picked up rather than pay the government collectors.

Farmers in Jiaxing were reported to have raised a total of 7.34 million pigs last year. Of that number, more than 325,000 dead pigs were disposed of properly at 573 stations in the city.

According to the local government, death rates are around 10 percent which meant that many more dead pigs were unaccounted for.

Fewer dead pigs are being dumped now due to stricter supervision after more than 10,000 carcasses were fished out of the Huangpu River in Shanghai earlier this year.

Last month, a pig farm in Jiaxing confessed to dumping dead pigs in the river but didn't specify numbers, according to Xinhua.

But the Jiaxing city government insisted that not all the pigs had been dumped by its pig farmers.


http://www.shanghaidaily.com/nsp/Metro/2013/04/02/Illegal%2Bdead%2Bpig%2Btrade%2Bput%2Bpork%2Bon%2BShanghai%2Btables%2Bfor%2Byears/

#H7N9: Bird flu deaths 'no connection' with pigs

 By Cai Wenjun  |   2013-4-2
NO bird flu virus was found in dead pig samples from the Huangpu River that provides drinking water to residents in Shanghai where two men died in the first human infections of a new avian influenza strain, the city government said yesterday.

The two patients, 87 and 27 years old, became ill with fever and coughs in late February and died in early March, suffering from severe pneumonia and difficulty in breathing.

The two were confirmed to be infected with H7N9 avian influenzas.

Yesterday, the Shanghai Animal Disease Prevention and Control Center tested 34 samples of pig carcasses pulled from the Huangpu River and found no bird flu viruses, the city government said in a statement.

Microbloggers had aired suspicions the bird flu cases were related to the thousands of pig carcasses recently retrieved from the river.

Dr Lu Hongzhou, vice president of Shanghai Public Health Center and a leading infectious disease expert, said the pigs died in neighboring Zhejiang Province, where no H7N9 bird flu cases had been detected.

"Bird flu virus can mutate and cause new subtypes, but it has no connection with a pig disease or porcine circovirus," he said.

Meanwhile, the city government is to step up the monitoring of flu and pneumonia cases following the deaths.

However, the World Health Organization says there is no evidence the H7N9 virus which killed the men can be transmitted between people.

Shanghai health officials said hospitals reported 24,000 flu-like cases in the first three months of this year, 43.28 percent fewer than in the same period of last year.

No hospital, flu laboratories or fever clinic in the city detected cases of SARS, human infection with the H5N1 bird flu virus or a new SARS-like corona virus in patients with unexplained pneumonia between November 15 and March 31 this year.

From January 1 to March 29, 130 hospitals with fever clinics reported that the number of patients with both fever and lung infections dropped by 4.34 percent from the same period of last year, the city government said.

A woman in Anhui Province also contracted the H7N9 virus in early March and is in critical condition.

"At this point, these three are isolated cases with no evidence of human-to-human transmission," the WHO's representative in China, Dr Michael O'Leary, told a news briefing in Beijing.

"A new virus tends to be more virulent in the beginning. Either it is going to become a truly human virus, in which case we have to start dealing with it regularly, or it is going to be primarily an animal virus with just a rare human case," O'Leary said.

There had been some complains that the authorities took too long before announcing the deaths on Sunday. O'Leary said the government acted properly as the deaths needed to be investigated, Reuters reported.

"China actually for a long time has been reporting promptly and openly. I think SARS was a turning point globally for that sort of thing," he said, referring to the 2003 epidemic where official numbers of cases were later dramatically revised upwards.

People buying poultry at a Shanghai market yesterday said that they hoped the government would be quicker to report new bird flu cases.

"In the future, no matter what it is, the government should make it public quickly and let the people know early. That way they can prevent it themselves", said shopper Zhang Zhili, 60.


http://www.shanghaidaily.com/nsp/Metro/2013/04/02/Bird%2Bflu%2Bdeaths%2Bno%2Bconnection%2Bwith%2Bpigs/

China: Dead Duck, Dead Pigs

[Shortly after my last post on the dead pigs in the Huangpu River, located here, there were 1,000 Ducks found dead in the Nanche River, in Pengshan County, Sichuan Province.  I will repost this excerpt from the last post I made on the dead pigs:
Hog farmers have told state media that the dumping of swine carcasses is rising because police have started cracking down on the illicit sale of pork products made from dead, diseased pigs. ]

March 25, 2013

Around 1,000 dead ducks have been pulled from a river in southwest China, local officials say.
Residents found the dead ducks in Nanhe river in Pengshan county, Sichuan province, and alerted the environmental department, they said.

Local residents and livestock were not at risk as the river was not used for drinking water, officials added.

The news comes as the toll of dead pigs pulled from Shanghai's Huangpu river passed 16,000.
Speaking in an interview with China National Radio on Sunday, Liang Weidong, a deputy director in Pengshan's publicity department, said that the authorities were first made aware of the ducks on Tuesday.

Officials discovered over 50 woven bags which contained the carcasses of around 1,000 ducks in the river.

continued:  http://www.bbc.co.uk/news/world-asia-china-21921145