Vietnam: For the first time: U.S. chicken eggs can prevent flu H5N1 and H1N1

06/06/2010

TP - Scientists have discovered that antibodies in chicken eggs in areas where poultry were vaccinated against influenza virus H5N1 can be used to prevent H5N1 infection in humans and this measure can be applied to against seasonal influenza and pandemic influenza H1N1 is present.

The team of Dr Nguyen Huu Huan, the International Vaccine Institute (IVI) partnered with Control Center & U.S. Chamber Translation (CDC), the Yonsei Konkuk University in Seoul, South Korea and Animal Health Diagnostic Center central Vietnam, has successfully tested the effect of antibodies from egg collection sold at supermarkets and chicken farm in Vietnam resistant H5N1 virus on experimental mouse model.

Expert immunologist, Dr. Nguyen Huu Huan, chaired the study, said: "The results showed, the use of antibodies in chicken eggs (IgY is abbreviated in English) collected from the National birds have been vaccinated to prevent the spread of highly pathogenic H5N1 influenza virus. So this may be the safety measures, effective and inexpensive in preventing influenza viruses, including seasonal and pandemic influenza H1N1 flu now. " This work has been published in international scientific journal PLoS ONE 13th - 4-2010 http://www.plosone.org/article/info:doi% 2F10.1371% 2Fjournal.pone.0010152

Based on the fact most of Vietnam's poultry have been vaccinated resistant H5N1 avian influenza vaccine, scientists have extracted IgY antibodies from chicken eggs purchased from the chicken farm and the supermarket in Vietnam. When taken IgY antibody to the airways of mice infected with the virus before causing H5N1, all the mice are healthy and show no signs of infection. Moreover, a different group of mice after infection with influenza virus H5N1 causes but were treated with IgY antibodies have a full recovery.

Possible H1N1 pandemic influenza prevention
IgY antibodies can be used in the form of nose drops or liquid solution while animals treated for throat. The method of passive immunotherapy can be applied to the prevention of seasonal influenza or an influenza pandemic caused by H1N1 is now immune to the poultry, egg and then harvest Extracts IgY antibody.
Dr. Cecil Czerkinsky, immunology specialist, vice Vaccine Institute International Institute (IVI) said: "The research forms the foundation for methods of passive immunity to pandemic influenza prevention, especially for the implementation of mass vaccination program for poultry. "

"This is a very interesting study. This method can be done in developing countries, does not require facilities and expensive equipment that could save millions of people ", Prof. Dr. David Briles, a leading microbiologist at the University Study of Alabama, Birmingham, USA, said.
Dr. Nguyen Huu Huan said, actually, IgY antibodies have been used in some countries to treat certain intestinal infections, but have not been tested in the prevention of influenza. Based on practical poultry in Vietnam have been vaccine-resistant H5N1 avian influenza, he proposed the idea of extracting IgY antibodies in chicken eggs are available to buy in Vietnam to prevent and treat H5N1 flu. Ph.D. presented and discussed in scientific works of this annual meeting of immunologist Vietnam in 2010.
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