Showing posts with label H3N2v. Show all posts
Showing posts with label H3N2v. Show all posts

Wednesday, January 4, 2012

New Flu Strain Puts Pork Industry on Alert After 2009 Pandemic #h5n1 #H3N2 #BIRDFLU

[This is also named S-OtrH3N2 and we have information on it located in the right side-bar]

New Flu Strain Puts Pork Industry on Alert After 2009 Pandemic

Wednesday, 04 Jan 2012 10:25 AM
A new flu virus thought to have originated in pigs has agricultural producers on alert two years after a swine flu pandemic caused sales to drop and disrupted U.S. pork exports.
Twelve people in five states have been infected, with three hospitalized, according to the Centers for Disease Control and Prevention in Atlanta. At least six reported no recent exposure to pigs, suggesting “limited human-to-human transmission,” according to the report. Eleven of those stricken were children.

The virus may not become as prevalent as the 2009 variant, known as H1N1, which led to as many as 89 million cases and 18,300 deaths in the U.S. in the first flu pandemic in more than 40 years, according to the CDC. Still, livestock producers are concerned that consumers may fear they can get a potentially lethal disease from eating pork. Flu is transmitted through droplets of infected body fluids when people cough, sneeze or talk.

“It’s always something that we need to keep an eye on, that it doesn’t get more severe or spread more quickly,” Liz Wagstrom, chief veterinarian with the National Pork Producers Council, which has offices in Des Moines, Iowa, and Washington. “It’s very important the public understand you can’t get flu from eating pork.”

Import Ban
During the H1N1 pandemic, China and Russia closed their markets to U.S. pork and industry revenue was estimated to have fallen by nearly $2.2 billion in the last eight months of 2009, according to the council. The H1N1 strain contained genetic material from five different flu viruses, including North American swine and bird flu and two swine flu viruses found in Europe and Asia.
The Des Moines, Iowa-based National Pork Board, which conducts research on pork and promotes the food, has sent out alerts, said Wagstrom. Veterinary labs that test samples from sick pigs are on the lookout for the strain, she said.

U.S. agencies are not referring to the new strain as swine flu, mindful of the popular description of H1N1 that upset markets and producers. Such illnesses contain a genetic mix of viruses seen in pigs, birds and people and get the moniker because the overall structure is the type that affects pigs.

“We are aware of the pork industry’s concerns,” said Jeff Dimond, an agency spokesman, in an interview.
CDC has “gone overboard” not to use the description, he said.

Genetic Similarity
The new virus, called H3N2v, contains a gene from the 2009 variant, according to the CDC. The agency is “taking this situation very seriously” and has increased surveillance in areas where cases occurred, according to a Dec. 9 CDC report. As a precaution, a candidate vaccine has been developed and provided to manufacturers so they can begin production if necessary, according to the report.

The strain has been detected in Indiana, Iowa, Maine, Pennsylvania and West Virginia, according to the Atlanta-based health agency.
Despite the added surveillance, government scientists haven’t made conclusions about the durability of the new strain.
All the people sickened have recovered and no continuing transmission has been detected, according to the CDC. Human immunity may be a concern because it’s a new virus.

Could Get Legs’
“This particular strain could get legs, so to speak, or just die out,” Dimond said.
The strain isn’t too worrisome because it doesn’t seem to be spreading quickly, said Peter Katona, associate clinical professor of infectious diseases at the University California, Los Angeles, in an interview.
The reported cases have prompted “concern, but I wouldn’t say it’s super high,” John Treanor, chief of the infectious disease division at the University of Rochester Medical Center in New York, said in an interview.
It’s important to track such viruses so the U.S. can respond if they begin spreading rapidly and become more virulent, he said.
Will the viruses be able to emerge from pigs into humans and cause another pandemic in humans?” said Treanor. “That’s why we keep track of what kinds of viruses are emerging.”

Work Begins on Possible Vaccine Against Novel Flu Bug H5N1 #H3N2 #BIRDFLU

H3N2V whhich was mentioned in my vid..

Work Begins on Possible Vaccine Against Novel Flu Bug

Robert Lowes
January 4, 2012 — Taking no chances, the US Centers for Disease Control and Prevention (CDC) is laying the groundwork for a possible vaccine against a novel strain of a swine influenza virus that has surfaced in 5 states and sickened 12 individuals, mostly children, since July 2011, an agency official told Medscape Medical News Tuesday.

The strain, designated A(H3N2)v, is a variant of the A(H3N2) virus that circulates among humans on a seasonal basis. What makes it a variant is a gene from the pandemic 2009 influenza A(H1N1) virus that codes for matrix proteins found in the viral shell.

In Indiana, Pennsylvania, and Maine, the virus appeared to have spread from pigs to humans, according to the CDC. In Iowa and West Virginia, however, the evidence suggests limited human-to-human transmission. In general, the novel virus is no more severe than ordinary seasonal influenza, and all the people infected with it have recovered.
The CDC is encouraging public health agencies and clinicians to collect more nasopharyngeal swabs from patients presenting influenza-like illness for testing to determine whether the novel virus may be spreading on a sustained basis.
CDC spokesperson Thomas Skinner told Medscape Medical News that the agency already has prepared a "seed virus" obtained from A(H3N2)v specimens that drug manufacturers can use to develop a vaccine if needed. Preparing a seed virus involves genetically manipulating specimens to incorporate preferred features.
Because the new virus is different enough from the seasonal viruses now in circulation, the seasonal influenza vaccine for 2011-2012 "is not expected to provide significant protection" against the newcomer, according to a Morbidity and Mortality Weekly Report that the CDC published on December 23. The trivalent seasonal vaccine is formulated to protect against the 2009 pandemic virus, the regular A(H3N2) virus, and an influenza B strain.
CDC Could Be Preparing for 2012-2013 Influenza Season
So far, the evidence does not suggest that the A(H3N2)v strain is spreading freely through communities, which would create the need for a vaccine. The bug could fizzle out, according to Christine Layton, PhD, MPH, a public health researcher and influenza pandemic expert at RTI International in Research Triangle Park, North Carolina.
Dr. Christine Layton
"There have been past instances where a novel virus comes up and then goes back down," Dr. Layton told Medscape Medical News. "There may be something about the virus that [prevents] sustained human-to-human transmission."
If the A(H3N2)v virus ever takes off, she said, drug manufacturers would have a tough time turning out a corresponding monovalent vaccine "at the drop of a hat." Influenza vaccines are still mass-produced, for the most part, by being grown in chicken eggs. Together with testing and licensing a vaccine, this process easily can last 3 to 4 months.
A more likely scenario, said Dr. Layton, would be incorporating an A(H3N2)v strain in the trivalent seasonal vaccine for 2012-2013, assuming the novel virus becomes that much of a threat. Each February or so, an advisory panel of the US Food and Drug Administration (FDA) recommends 3 strains of influenza that should make up the seasonal vaccine for the coming fall on the basis of what it expects to see circulating then. The CDC then develops the seed viruses for these 3 strains, which the FDA distributes to vaccine makers.  http://www.medscape.com/viewarticle/756348