Saturday, February 25, 2012
TT - On 25-2, Truong Van Duc - The Director of Veterinary Binh Duong - validate the model tests showed that patients Phu Truong Son (22 years) positive for influenza A/H5N1.
According to authorities, Son is a free laborer born in Hoang Hoa district (Thanh Hoa), about a year now Son into their home as his uncle Tran Dinh Hau (living in Phu Loi, Thu Dau Mot town Binh Duong). Thin First Year Nham Son home food festival, on the back of Binh Duong 8-2.
According to the patients during their stay at home as well as the time returned many times Binh Duong Son eat chicken, duck and duck.
On 17-2, Son of the disease. Before the disease a few days, Son duck meat purchased from Cu Chi (Vietnam).
23-2 To date, Son was brought into Tropical Diseases Hospital, City of treatment.
* Add 128 hand foot and mouth disease cases in Vietnam in the first eight weeks (from 16 to 22-2), according to the HCM City Department of Health, bringing the total number of cases from January to today to about 600 cases (one death in the District 8), up dozens of times over the same period last year. http://tuoitre.vn/Chinh-tri-Xa-hoi/479401/Binh-Duong-phat-hien-ca-nhiem-cum-gia-cam-o-nguoi.html
He went to school (a University exists there) or work in Binh Duong Province. His address for that location is 8th St. Phu Loi, Thu Dau Mot.
He came home for TET, a food festival, to Di An Town, Thanh Hoa Province.
He arrived home on 2/8. He became sick on 2/17.
He is back down South in Ho Chi Minh City Hospital.
His onset occurred down South.
The yellow postmark is just to show you where Thanh Hoa Province is.
Click on Map for enlargement.
That patient named Phu Truong Son (born 1990, native Hoang Hoa district, Thanh Hoa province), staying in Phu Loi, Thu Dau Mot town ...
25/2, Xu Tan Wednesday, Health Department spokesman confirmed Binh Duong Province have found a positive case of influenza A/H5N1.
That patient named Truong Phu Son, born 1990, native Hoang Hoa district, Thanh Hoa province, staying at Tran Dinh Late in the 12th, 8th street, Phu Loi, Thu Dau Mot town. Before that, after the return home for Tet Pacific working for 3 weeks, on 17/2 recently, Son has high fever, difficulty breathing and was taken to hospital in the town Vu Cao Di An, examination and treatment, but more severe disease on changes in the respiratory tract should be moved to the Corps Hospital four patients continued treatment but still no relief.
On 24/2, after transfer to Hospital for Tropical Diseases, Ho Chi Minh City, the samples of laboratory-Son patients found positive for influenza A/H5N1. Soon, Son of patients treated have been quarantined. Afternoon of 25/2, Center for Preventive Medicine Pacific in collaboration with the Pasteur Institute in Ho Chi Minh City to conduct tests at the hospital Vu Cao Diseases Polyclinic and Hospital Corps 4, to review those directly exposed patients with Phu Truong Son to be isolated, blood test monitoring.
The same day, Pacific health home inspection Hau Tran Dinh, in the 12th, 8th street, Phu Loi, Thu Dau Mot town and also apply those isolated from direct contact with patients This person at the same time conducting spraying chemicals, decontamination areas Son patients living accommodation and medical treatment room.
According to Friday, patients from Thanh Hoa Son - local recurrence is a bird flu outbreak. But as a precaution and initiative, the health sector are looking to review the origin influenza A/H5N1 infection from patient to determine the source of infection arising in any locality.
Mr. Ta Trong Khang, deputy medical thy Pacific Department, said the review took nearly 100 serum samples in poultry in the area at the 12, KP8, Phu Loi, Thu Dau Mot town, to be tested identify measures coincide, detoxify in this neighborhood. http://www.baomoi.com/Home/SucKhoe/www.vietnamplus.vn/Binh-Duong-Phat-hien-ca-nhiem-cum-gia-cam-H5N1/7949467.epi
Sunday, 26.02.2012, 01:36 (GMT 7) (SGGP). - Afternoon 25-2, the Veterinary Department of Binh Duong Province, said veterinary officials are conducting tests of serum samples for raising poultry in eight people in town, Phu Loi (town Prime Dau Mot, Binh Duong province), where the newly discovered cases of bird flu (influenza A/H5N1) in the first in the province.
Earlier, on 23-2, Phu Truong Son patients (SN 1990, Thanh Hoa countryside, staying in the 12, eight quarters, Phu Loi) is transmitted to Tropical Diseases Hospital (HCMC) after treatment presents with influenza A/H5N1. The sample showed him positive for influenza A/H5N1 Son. Son resident at the above address about a year, a week before Tet, home to the food festival in Thanh Hoa, Binh Duong and then back into the disease.
It's not his Son to identify influenza A/H5N1 in any locality. http://www.sggp.org.vn/ytesuckhoe/2012/2/281977/
Friday, February 24, 2012
|Thai Chicken die down river along Highway 48B past the U.S. and Quynh Laundry Bridge Town.|
Ministry of Health through the Directorate General of Disease Control and Environmental Health, announced a new case of H5N1 have been confirmed by the Center for Basic Biomedical and Health Technology, Balitbangkes.
Case on behalf of DWM (male, 12 years) resident of Badung, Bali. Dated February 11, 2012 fever symptoms develop, see a doctor in private clinics and hospitals. On February 16, 2012 the case was being treated RS. Because of increased shortness, on February 20, 2012 the case was referred to the Referral Hospital Bird Flu, but eventually the case died on February 21, 2012.
Epidemiological investigations have been conducted in the home and neighborhood environment cases by the local Health Department with the results of risk factors is unclear.
With the increase of these cases, the cumulative number of bird flu in Indonesia since 2005 until this news was broadcast on 186 cases with 154 deaths.
Director General of Disease Control and Environmental Health Yoga Aditama Prof.dr.Tjandra as the focal point of the International Health Regulations (IHR) has been informed about the case to the WHO.
This information is published by the Center for Public Communication, Secretariat General of the Ministry of Health. For further information please contact via telephone: 021-52907416-9, fax: 021-52921669, Call Center: 021-500567 and 021-30413700 or e-mail address puskom.publik @ yahoo.co.id; info @ department of health . go.id; firstname.lastname@example.org.
The examination of patients suspected of bird flu at the General Hospital (Hospital) Dr. Doris Sylvanus was negative. Hospital patients in Palangkaraya, Central Kalimantan were previously treated in isolation but has now been allowed to mingle with other patients.Deputy Director of Medical and Hospital Care Dr Doris Sylvanus, Irly Yulia in Palangkaraya, Friday (24/02/2012), said , ie the patient M, was dik was excluded from the isolation room on Thursday afternoon yesterday. The patient was rushed to hospital on Saturday (18/02/2012) and immediately put in isolation. According Irly, M can only be added to the usual care after waiting for the results of tests carried out in Jakarta. Along M, treated three members of his family. "If all the members of the family M, was out of the isolation room last Wednesday," he said. They are expected to be returned to the village Murui homelands, Central District of Kapuas, Kapuas, Central Kalimantan, next week. At present, the condition of M and the members of his family quite well. They do not have a fever, cough, runny nose, with a normal appetite. "We are still awaiting the results of viral culture. result is still only known for a long time, about three weeks," said Irly.
Pasuruan (beritajatim.com) - Five people from bird flu suspect Petamanan Village, District of South Bugul, Makati City turned out to be negative. The results of this test, issued by the Central Health Laboratory (BBLK) in Surabaya in East Java. They were found not infected with bird flu virus after laboratory tests on the throat and nasal mucus and blood 3 times, the results are negative. With the release of test results, it is hoped the public not to panic anymore. "all five of them negative. There is one referred to, may be the suggestion he was scared. That was the end result is negative. With these test results, meaning that so far bird flu infection from animals to humans has not been there, "said Bambang Pramod on Friday (02/24/2012). Secretary of Makati City Health Department explains, the five people suspected of bird flu is just a fear that too much. Because the resident birds have previously tested positive of bird flu based on rapid test results. "They just have regular flu. It's not something that is considered severe. Because, if people are exposed to the bird flu virus, symptoms usually experience shortness of breath, coughing. and that this virus is under attack organs such as lungs, "he said. [bec / kun]
Posted by Declan Butler
Canada this month announced that any research on mammalian-transmissible strains of the H5N1 avian flu virus in the country’s labs would need to be done at the strictest level of biocontainment, biosafety level 4 (BSL-4). It’s the first country to issue a biosafety rating following the creation of such H5N1 strains in two recent controversial studies (see Nature News Special: Mutant Flu).
The question of which biosafety rating is appropriate for research on the new strains was highlighted as crucial by an expert meeting convened in Geneva last week by the World Health Organization (WHO). The new, modified H5N1 strains are held at Erasmus Medical Center in Rotterdam, the Netherlands, and at the University of Wisconsin-Madison, in two BSL-3-enhanced facilities (the second highest biocontainment level), and the WHO described these as “well-established research facilities with high security and high safety“. But it also recommended that regulators “urgently” review the biosafety and biosecurity conditions under which further research on such strains is conducted, and that until that’s done, the strains should stay where they are and not be shared with other labs.
In biosafety assessment, pathogens are classified in terms of their ‘risk group’ (RG) on a scale of 1–4, where 4 is the highest, on the basis of an assessment of the relative threat they pose to people. They are also classified in terms of the biological containment levels needed, again on a scale of 1–4. What can be a bit confusing is that although required biocontainment levels for various research on a pathogen largely mirror the risk-group rating, they don’t necessarily equate with it. Some types of research may be permitted at a lower biocontainment level than their risk group, if it’s assessed that the research can be done safely with less-restrictive precautions. As the WHO explains, biocontainment level designations are “based on a composite of the design features, construction, containment facilities, equipment, practices and operational procedures required for working with agents from the various risk groups”.
Barry Bloom, a researcher and former dean at the Harvard School of Public Health in Boston, Massachusetts, also emphasizes the importance of training. “Security in handling dangerous pathogens is, in my view, less a function of the physical containment facilities than the training, experience and competence of the scientists working with them,” he says.
Some flu researchers are concerned that work on mammalian-transmissible H5N1 viruses will be severely hampered if it is restricted to BSL-4 laboratories, because BSL-4 conditions are much more constraining than BSL-3 labs, and because there are only a few dozen BSL-4 labs worldwide. Other experts feel that such high containment is essential, given the risk that any escape of the viruses could cause a H5N1 pandemic (see Fears grow over lab-bred flu.)
Whatever biocontainment levels are eventually decided as appropriate by the relevant authorities, many researchers are concerned about the proliferation of such mammalian-transmissible avian flu strains: as more labs work on them, the risk of release — accidental or intentional — goes up. Bloom says that he hopes that the number of labs allowed to work on them “would be limited, transparently identified, and monitored for safety under the aegis of an international body such as WHO”.
Declan Butler asked Sandra Fry, director-general of the Public Health Agency of Canada’s Pathogen Regulation Directorate, and Marianne Heisz, head of the directorate’s Office of Biosafety Programs and Planning, how the agency reached its decision to classify work on the new lab strains as requiring BSL-4 (note that Canada uses the term ‘CL’ in place of BSL) facilities.Read the Q&A under the fold.
[continued - click on title for full article]
Thursday, February 23, 2012
[We have posted the research paper from Mount Sinai School of Medicine here]
23 Feb 2012 20:31
Source: reuters // Reuters
* U.N. agency WHO estimates death rate topping 50 percent
* Study suggests far lower rate, apparently under 1 percent
* Critics cast doubt on new study, WHO defends its figures
* Adds to controversy over publishing bird flu research
By Sharon Begley
NEW YORK, Feb 23 (Reuters) - Bird flu may be far less lethal to people than the World Health Organization's assessment of a death rate topping 50 percent, scientists said on Thursday in a finding that adds fuel to the heated controversy over publication of bird flu research.
Scientists led by virologist Peter Palese of Mount Sinai School of Medicine in New York argue in an analysis published in the online edition of the journal Science that the WHO, a U.N. agency, is calculating the death rate using an estimate of human bird flu cases that is simply too low.
Palese and his colleagues did not offer a specific death rate for people infected by bird flu. But based on figures cited in their analysis, the rate appears to be under 1 percent.
The WHO stood by its calculations and some experts criticized the Palese team's findings, saying they were based on misleading data. As of Thursday, the WHO counts 586 cases of people infected by bird flu. Of those, 346 died, for a fatality rate of 59 percent.
Palese declined requests for an interview, and asked his co-authors not to speak to reporters, according to the Mount Sinai press office.
continued - click on title for complete article.
2012.02.24 12:00 am
The mainland microblogging came near Beijing, Hebei Baoding, the city's People's Liberation Army 252 Hospital with SARS death. However, sources pointed out that the hospital staff an inquiry, denied that the PRC CDC staff did not receive the message. Baoding Health Bureau responded that in the afternoon, the hospital of the municipality has no SARS epidemic. Hong Kong media reports related to patients with the common flu, no deaths, the hospital is operating normally. [link to udn.com]
Transferred the patient was infected with SARS in Baoding, Hebei People's Liberation Army 252 Hospital, last night, armed police guard, but not tense atmosphere, the hospital as usual. (Photo by Ming Pao reporter)
[Ming Pao] Mainland online has spread refers to the Chinese People's Liberation Army 252 Hospital, Baoding, Hebei treated over 100 patients with suspected SARS. Centre for Health Protection in Hong Kong yesterday to contact the Ministry of Health, Ministry of Health, the initial recognition is not the SARS epidemic, and later in the relevant Mainland authorities will be sent and informed of relevant news. The reporter last night to reach Baoding 252 hospitals, but no armed police guard, but not tense, the hospital as usual.Hong Kong Centre for Health Protection, said the Ministry of Health will continue to closely follow up the matter and to monitor the latest developments.
The Health Ministry said the non-SARS in Hong Kong, close follow-up
Mainland recently circulated on the Internet an information, refer to "Baoding, Hebei People's Liberation Army 252 Hospital admitted more than 100 people have been fatal SARS variation, the first patient in Baoding Qingyuan Wing school to check out, now hospitalized most of them are young soldiers, because that is the People's Liberation Army hospital, before the onset to the south training.
Mainland netizens Baoding, 252 hospitals were closed, due to the emergence of mutant virus in the micro-Bo said. Mainland Sohu microblogging query to the local staff, the hospital said the seal hospital and everything is normal, hospital nurses said there was no variation of the virus, but the recent increase in fever patients.
Armed police guarded the Baoding public to wear masks
The reporter last night to reach Baoding 252 hospitals, but no armed police guard, but not tense, the hospital as usual. A security Wang said recently the weather is cold, flu patients increased, but not of SARS, "(SARS), are not our security guarding, the whole hospital will be martial law. The reporter also asked several Baoding public had heard of SARS rumors, but can not guarantee that the news is true that the flow of people gathered at the train station, streets and other places, and no some people wearing masks and other preparedness.
HA Head Infection Control Officer Dr Tsang said that Hong Kong already has a strain of SARS mechanisms and facilities, the HA has 1400 negative pressure isolation beds of infectious diseases, laboratory SARS virus is a quick test agent, a few hours there will be results.Isolation beds to be requisitioned by the hospital for other services, if the SARS outbreak, the hospital only three days can reply to the isolation ward of the function. He said there is evidence of the SARS outbreak, the signs of HA in conjunction with the Centre for Health Protection (CHP) activated the emergency response mechanism, but worry about the most difficult to find the first incidence of the source.
CHP spokesman said that a comprehensive system of channels of communication between Hong Kong and the Mainland, including the notification mechanism of the Severe Acute Respiratory Syndrome SARS, to ensure the timely exchange of important news and information on infectious disease events, and the outbreak. http://news.sina.com.hk/news/3/1/1/2586776/1.html
network rumored to nine years ago, the SARS outbreak caused worldwide panic to reproduce Hebei The rumors that Hebei one hundred soldiers fever hospital, there was one death, the hospital suspected that soldiers stained the "evil", blocking the whole floor. The rumors of the outbreak more than a week, the Chinese Ministry of Health yesterday before opening to deny. CDC also has to verify, initially ruled out the possibility of these soldiers stained the SARS.
..The hospital was sealed floor
SARS comeback rumors in Hong Kong Golden Forum, Sina microblogging and Baidu Post! Crazy mass refers to the users, 17 Qingyuan Wing school the whole even the soldiers to eat bad things, high fever, sent to the Chinese people, Baoding, Hebei People's Liberation Army 25 two hospitals, the hospital suspected that soldiers stained the SARS patients treated in isolation, it is said the patients are mostly young soldiers.
Users "sugar pot" refers to the 25 two hospital floor isolation, armed police guard. Sina microblogging has blocked the "People's Liberation Army 25 Hospital", the string search of the "atypical pneumonia".
Clarification of late by the authorities failed to convince the public doubts, users refer to: "If the rumors, the rumor is it, why the relevant search keywords are also banned.
"Apple" last call 25 2 hospitals to verify the hospital Ms. Chu refers to have heard "rumors", Hospital Respiratory are normal to see the doctor, did not seal the floor issue.
"Beijing does not tense deadWang Jixiang, president of Baoding, Hebei Taiwan Business Association, said in an interview before leaving on the 21st of Baoding, have not heard the news at the local, he said that Baoding close to Beijing, if the outbreak of the SARS epidemic, Beijing authorities are not dead. Jih-Haw Chou, I Department of Health, CDC director, said last night, checking the reply is initially ruled out the possibility of these soldiers stained the SARS. [link to tw.nextmedia.com]
Recently, rumors of the Severe Acute Respiratory Syndrome (SARS) cases on the Hebei Province, the spokesman for the Department of Health Centre for Health Protection has successfully contacted the Ministry of Health, and the initial recognition by the Ministry of Health is not a SARS outbreak, the relevant Mainland authorities will later send a message notification.
The CHP will continue to work closely with the Ministry of Health to follow up the matter, and to monitor the latest developments.
[link to www.singtao.com]
Hebei startling news of the return of SARS
Feb. 23 (CNA) The Centers for Disease Control (CDC) said Thursday that there is
no SARS outbreak in China, despite unverified information circulating on the
The Chinese health authorities have clarified that there is no SARS outbreak within its territory, said CDC Deputy Director-General Chou Chih-hau.
The Chinese authorities will provide information to the CDC regarding the rumor on Friday, as its office in charge is already closed, he added.
Many Chinese Internet users have voiced concerns over a possible pandemic of severe acute respiratory syndrome (SARS) in a military hospital located in Hebei Province, according to a local daily newspaper.
SARS is a respiratory disease caused by a virus that infects the lungs and causes difficulty in breathing. Common antibiotics have proven ineffective against SARS and patients must rely on clinical treatment to recover.
Although the Chinese government has yet to officially deny the rumor, bloggers alleged that hundreds of patients have been hospitalized in isolation wards and at least one has died from the fatal disease, the newspaper report said.
In the past, China's government has records of covering up news about infection cases.
There are so far no reports from Hong Kong, which was one of the areas hardest hit by the SARS pandemic between 2002 and 2003, or the rest of the world.
While customs officials are equipped with sensors to detect a fever, a typical symptom of SARS, Chou said Taiwan has also established more than 1,000 isolation wards and facilities, a lesson learned from past experience.
SARS caused about 70 deaths in Taiwan a decade ago, including a number of medical staff in charge of patients, according to Chou.
"We are taking a precautious attitude toward this,”he said.
Need a map strainAt the meeting, Mr. Hoang Van Nam, Director of Animal Health, said that from early 2012 until now, bird flu has occurred in the area 36 communes of 29 districts of 12 provinces and cities in the country. Total number of poultry deaths, disease and destruction is 51,900 children. This was not the phenomenon in some other localities including Hanoi, Ha Tinh, Nghe An appearance dead sick poultry but no test results for samples that have bird flu or not.
He describes, in general, mutation genetic mutations in the virus easily occurs due to environmental influences, both environmental, as well as vaccines that are not adaptive. Because, he added, the symptoms of bird flu virus is contagious in humans is not identical with each other.
In addition, the spread of bird flu virus is also questionable. Because, who contracted the virus directly or child is not a breeder cage, but other people who are not in direct contact with poultry. . "But this has not been shown to map its spread and has not been shown how the spread of the virus in humans," he said.
The Government, he said, need ekstrawaspada. mentioned, about 3 million people across Indonesia that each day in direct contact with poultry. "Give a vaccine that proved suitable landing field. This should be done so that no more harmful genetic mutations," he said.
Responding to terserbut, Director General of Animal Husbandry and Animal Health Ministry of Agriculture Gratitude Iwantoro said preventive measures taken to prevent the spread of bird flu virus from birds to humans. " "We continue to do several steps, including biosecurity, vaccination, and if necessary, until the stage of culling poultry infected with the virus," said Gratitude.
Thanks be mentioned, to date there are at least seven provinces are reported to have experienced the case of AI (Avian Influenza / Bird Flu) in poultry, namely Central Java (Sragen, Bradford), East Java (Lamongan), Riau (Pekanbaru), East Kalimantan (Panajam North Paser), Jambi (Jambi Muaro), South Sulawesi (Sidrap) and Jakarta (North Jakarta). . In the report, the number of dead birds were reported as many as 1073 birds.
By Thanksgiving, the potential spread of bird flu virus in the Jakarta area is still low. But he is asking the public for the circulation of the avian flu alert in Jakarta could happen with the entry of chicken and chicken from other areas. "About 800 thousand chickens per day of supply coming from other provinces to be cut and sold in Jakarta," he said.
Recorded the number of cases of AI in poultry nationwide in 2011 as many as 1411 cases, or about 122 cases per month, or 4 cases per day. The amount is lower than the previous year, namely in the year 2010 as many as 1502 cases and 2009 a total of 2293 cases.
He added that bird flu cases is usually an increase in the period January to April. . This is because, at that time, are entering the rainy season and floods that spread the virus tends to be higher. http://translate.googleusercontent.com/translate_c?hl=en&ie=UTF8&prev=_t&rurl=translate.google.com&sl=id&tl=en&twu=1&u=http://www.jurnas.com/news/53551/Perlu_Ada_Vaksin_Baru_Atasi_Flu_Burung/1/Sosial_Budaya/Kesehatan&usg=ALkJrhjhWM_FU_fql5Fa6GKYNoeexrbZlw
Peter Palesea,b,1 and Taia T. Wanga
Departments of aMicrobiology and bMedicine, Mount Sinai School of Medicine, New York, NY 10029
The ongoing controversy over publication of two studies involving the transmission in ferrets of H5N1 (H5) subtype influenza viruses and the recommendations of the National Science Advisory Board for Biosecurity to redact key details in the manuscripts call for an examination of relevant scientific facts. In addition, there are calls in the media to destroy the viruses, curtail future research in this area, and protect the public from such “frightening” research efforts. Fear needs to be put to rest with solid science and not speculation.
Is the Case Fatality Rate for Human H5
Infections Truly Greater than 50%? At the
heart of this controversy is the notion that
the case fatality rate for human H5 infections
is in the range of 50% to 80%. This
rate is derived from the list of H5 cases that
have been “confirmed” under World
Health Organization (WHO) guidelines;
the list tallies 573 cases in 15 countries (as
of December 15, 2011), with nearly 60% of
total cases resulting in death (28). The
frequency and certainty with which this
staggering fatality rate is reported is troubling
when one considers how the numbers
are generated; in order for a case to
be confirmed by WHO, a person must
have an acute, febrile respiratory illness
(temperature >38 °C/100.3 °F) with known
H5 exposure in the 7 days preceding
symptom onset and have molecular confirmation
of H5 infection by a WHO-approved
laboratory (e.g., virus isolation,
PCR, serology) (29). This definition does
not allow for asymptomatic infections and
essentially requires that a person actively
seek medical help at a hospital that is
equipped to draw samples and ship them
to an approved laboratory. Given that rural
populations in developing countries are
most commonly affected by H5 viruses, it
seems unlikely that even a small fraction
of the total number of infected cases has
been accounted for under the WHO surveillance
system. Also, the fatal cases that
have been reported are most likely caused
by mega-doses of H5 virus inhaled by the
patients, who are living in very close contact
with infected poultry. Transmission
involving small doses of virus (as observed
under regular aerosol transmission conditions)
may not result in overt disease. Of
the 10 largest studies of which we are
aware (N ≥ 500) (30–39), which document
seroevidence in humans for H5 infections,
two studies report no seropositivity and
the other eight report rates ranging from
0.2% to 5.6%; the studies are mostly
conducted in rural areas where H5 infections
have been previously documented
(30–39). Even if only a low percentage of
the rural population is asymptomatically/
subclinically infected, the case fatality rate
that is offered by the WHO—and that is
driving this controversy—is likely orders of
magnitude too high. This suggests that
more work should be done to determine
an accurate case fatality rate for H5 infections,
which takes into account mild
and asymptomatic cases.
Why These Papers, Why Now? The type of
work performed in the studies under
evaluation is quite common in virology
because it is a useful way to study molecular
determinants of virus adaptation, pathogenesis,
and transmission. The reasoning
behind the selection by the National Science
Advisory Board for Biosecurity of
these specific papers for redaction/censorship
seems somewhat arbitrary relative
to what has previously been published in
the field of influenza.
In 2005, the complete sequences for the
1918 pandemic influenza virus were published
in Nature and methods describing
the rescue of the 1918 virus were published
in Science (40, 41). In 2006, both
Science and Nature published reports of
specific mutations that enable the H5 viral
hemagglutinin to bind human, rather than
avian, tissues (42, 43). In 2012, a report
from the Centers for Disease Control
and Prevention that bears striking resemblance,
in principle, to the works by
Fouchier and Kawaoka was already published
in Virology; it describes mutations
in an H5N1 virus that confer airborne
transmissibility between ferrets (44).
Studies have also been published recently
that describe mutations enabling other
potential pandemic strains to transmit
between ferrets (45, 46) or that make
currently circulating virus strains more
These are a small fraction of studies
published during the past decade that
could have been considered controversial
(some were controversial at the time, but
all were published in full). We know from
studies like these that, for example, the
2009 pandemic vaccine protects against the
1918 pandemic virus and thus the 1918
strain is not a pandemic threat at this time
(48), nor would it be of any advantage for
a bioterrorist to lay his/her hands on it.
Other striking examples of achievements
based on the free exchange of potentially
controversial information are the elimination
of SARS corona virus in only 6
months and the fact that the dangers of
HIV have been dramatically reduced by
the development of effective antiviral
treatments. None of this would have been
possible without the uncensored exchange
of scientific data.
Poultry quarantine is not selling rampant in HCMC On 23-2, the threat of avian influenza A/H5N1 outbreak, public health threat, the National Steering Committee for prevention of avian influenza conference briefings online direct emergency work prevention in many localities across the country.
Strong risk of epidemic
Opening the meeting online, Deputy Minister of Agriculture - Rural Development Diep Kinh Tan expressed concern that the bird flu epidemic could break up on a large scale at any time due to favorable factors such as adverse weather, complex magazine, vaccines and disease prevention is not resistant virus emerged. "The local emergency departments should actively quell the outbreak, limited to the lowest level outbreaks arise and prevent spread, protecting people's health" - Qin noted.
Leaders of 12 provinces and city have bird flu Hai Phong, Bac Giang, Ha Tinh, Quang Nam, Quang Tri, Ha Nam, Hai Duong, Thai Nguyen and Bac Ninh, Thanh Hoa and Soc Trang and Kien Giang reported urgently implement measures to control anti-bird flu but are concerned that the risk of outbreak is inevitable.
Hai Duong province's leaders said the unidentified strain of virus, sense of hygiene is poor people, breeding bird control is not achieved
Thanh Hoa Province, the proposal is funded, supplies and money to the poultry.
Ha Tinh province concerned by the large density of poultry should risk the spread of disease from water is difficult to avoid. As leaders of Henan province, said provincial vaccine is used to combat bird flu virus is to take effect ...
According to Hoang Van Nam, Director of Animal Health, from the beginning of the year, bird flu has occurred in 30 communes of 12 provinces and city with a total of infected poultry, killed and destroyed more than 35,000 children , of which 85% are duck, chicken ... 13.9% is worrying, many birds were all immune, has variants virus, no vaccine - would fit. In the North, Central and Western Highlands, had virus variants are complex, resistant to vaccines. The Mekong Delta is also effective vaccines. Therefore, this proposed local injection of 100% for ducks, especially the upcoming winter-spring rice crop, pretty much run the same flock. Meanwhile, Tran Thanh Duong, deputy director of the Department of Preventive Medicine (Ministry of Health), said that the vaccine prevention of bird flu epidemic is just one measure, the effect is limited, protect only 40% -50% of the poultry
Chống dịch như chống giặc Epidemic as against the enemy
23-2 During the day, Vice Chairman Le Minh Tri City has convened emergency departments, branches and localities to direct instruction implementing Directive No. 18-2 on the rise 04/2012/CT-UBND strengthen measures to prevent and fight bird flu in the city. He stressed that this is Tri urgent task, not subjective neglect, if the situation that translation services are difficult to counter her husband.
He suggested that Tri district steering committee established or consolidation, implementation of the directive seriously. Forces related to tight control on the city markets have 135 bird markets; deploy forces to control movement of poultry gateway city barricades. Private City Health Department leaders must actively prepare for the health plan if avian influenza occurred in the city. The plan must be specific for human resources, material resources, equipment, medication and the MPC next week. "Anti-translated as against the enemy. Must urgently, urgent and drastic "- Mr Tri said.
Deputy Minister of Agriculture - Rural Development Diep Kinh Tan request ministries, sectors from central to local electrical performance of the Prime Minister on the prevention of avian influenza. Deputy Minister said that this is the major risk, not subjective. 7 suggest the central mission of prevention of avian influenza need to extend the work to date 15-3, to set up inspection teams to supervise local districts and communes. DAH forces quickly mobilized to decipher the genetic type of virus variants, progressive mapping of avian influenza and proposing measures to prevent and combat effectiveness ...
Disease is fatalAccording to authorities, from early 2012 until now, our country has had two deaths due to avian influenza A/H5N1 (implies Soc Trang and Kien Giang). Thus far in 2003 there were 121 cases of this dangerous type of flu, including 61 deaths. Recommended by the World health authorities show that the bird flu virus has variants, independent force, if the risk of infection to death was 100%. http://translate.googleusercontent.com/translate_c?hl=en&ie=UTF8&prev=_t&rurl=translate.google.com&sl=vi&tl=en&u=http://nld.com.vn/20120223115027621p0c1002/nguy-co-bung-phat-cum-gia-cam.htm&usg=ALkJrhgqwFQNNPYOwYp-6I1OiEqPitr-og
Bird flu more common and less lethal - study
The research could help soothe concerns about the potential for a deadly pandemic that may kill many millions of people, sparked by the recent lab creation of a mutant bird flu that can pass between mammals.
Researchers at Mount Sinai School of Medicine in New York analysed 20 previous international studies that tested the blood of nearly 13,000 participants worldwide.
They found that between one and two percent of those tested showed evidence of a prior H5N1 avian flu infection, meaning millions of people may have been infected around the globe.
The World Health Organisation's figures currently show just 573 cases in 15 countries since 2003, with 58.6 percent of those resulting in death.
The researchers said the WHO may be overlooking cases by focusing only on hospitalizations and severe illnesses, and recommended a new approach to calculating the true number of bird flu cases.
"We suggest that further investigation, on a large scale and by a standardised approach, is warranted to better estimate the total number of H5N1 infections that have occurred in humans,'' the authors wrote...
- AFP http://www.nzherald.co.nz/health/news/article.cfm?c_id=204&objectid=10787688
VNA - Nearly 7,000 birds fall sick or die must be destroyed.
communes, wards of Kien Thuy District, Anyang, and Tien Lang district in diameter, Hai Phong city. Nearly 7,000 birds fall sick or die must be destroyed. The number of poultry outbreaks, most recently on 21/2 on the flock of nearly 800 families [translated separately: "on ducks nearly 800 children [birds] of families] Dao Van Xoan (social Kien Quoc, Kien Thuy district) and 200 thousand of families [translated separately: "her family's ducks"] Vu Thi Loc (in social An Dong, An Duong district).
Mr. Nguyen Van Hung, deputy Department, the Veterinary Department of Hai Phong said: Most of the poultry plague, vaccines are not vaccinated. Besides, due to prolonged cold weather makes the resistance of the poor bird, easy to outbreaks. In addition, the opportunity before, during and after Tet, the transport of poultry in other provinces of Hai Phong city to many, leading to infectious diseases.
To encircle, prevent epidemic, veterinary Hai Phong Department is implementing 500,000 doses of vaccine injected in localities where the outbreak occurred and the surrounding area. However, the risk spread can still occur due to the outbreak of the last 21 days, some people still subjective psychology, service marks and no vaccine suitable for vaccination.
The rate of virus circulating in poultry in Vietnam is now at a higher rate than in previous years, with 4.13%. In particular, the four provinces with high risk of epidemic is Ha Tinh (with virus prevalence in poultry is 25%), Thanh Hoa, Ca Mau and Quang Ninh (15%).
With these factors, Vice Minister of Agriculture and Rural Development Diep Kinh Tan assessment of bird flu this year is very complex and wide epidemic risk is high.
Deputy suggested the local concentration epidemic spread: 100% Destruction of infected poultry, disinfection and hygiene epidemic areas and setting up checkpoints to prevent the movement of poultry production poultry outbreak outside.
Besides, the Ministry of Health has identified 2 cases the patients died of H5N1 bird flu and are related to dead poultry.
"But the identification of bird flu outbreak in the locality now almost behind. Local government stupid, do not know that bird flu outbreak in their area. Only when there is death in humans, health authorities back to the province is testing a new local source of infection that any outbreak, "said Tran Thanh Duong, Deputy Director of preventive medicine evaluation.
Said senior agent of the Ministry of Agriculture Subhi Jumaili that dozens of bird flu infections have been recorded in Karbala recently.
Jumaily said, "told all of Iraq" on Thursday that high numbers of injuries in Karbala continued during the past few days despite the precautions taken by the Ministry of Agriculture in the health institutions.
He added that the ministry has to take samples from these birds and sent to the Scientific Organization of Animal Health to ensure that the incidence rate is it is mild or serious.
He added that the Ministry of Agriculture has asked the concerned authorities to prevent imports of poultry from Iran because of the emergence of many injuries from bird flu in the province until the arrival of the results of laboratory tests of the organization.
WHY DO we study flu? So we can protect ourselves from it. We've long since learned that H5N1 bird flu poses real reasons for concern; more recently, that it really does have the potential to become a nightmarish airborne plague. How should we react?
Not by delaying the publication of the research, for fear that it will aid supposed bioterrorists (see "Publish lethal flu virus work, says WHO"). There is surprisingly little evidence that such a threat exists. But there has long been a great deal of evidence that the threat of pandemic flu exists.
It is high time we ended it. We know existing flu vaccines, which date back to the 1950s, won't do the job. A vaccine that works against all types of flu - pandemic and seasonal - could. And promisingly, we have made some progress in this direction.
Yet with no commercial route to market, and regulators unable to agree on testing protocols, investment in universal flu vaccine is waning. If half the energy that went into seeing bioterrorists behind every Petri dish was expended on overcoming these obstacles, the squabble over publishing H5N1 research would become what it should be: purely academic.
Dosing livestock with antibiotics can be bad for farmers' health. A strain of MRSA that causes skin infections and sepsis in farm workers evolved its resistance to antibiotics inside farm animals.
The ST398 strain of MRSA first appeared in 2003 and is prevalent in US livestock. Humans who pick it up from animals can become dangerously ill, but it cannot yet spread from human to human.
A team led by Paul Keim of the Translational Genomics Research Institute in Phoenix, Arizona, sequenced the genomes of 88 closely related strains of Staphylococcus aureus, the bug that can become MRSA. Their findings suggest that ST398 was originally a harmless strain living in humans, which migrated into livestock where it acquired antibiotic resistance.
For some time microbiologists have been concerned that giving large amounts of antibiotics to livestock can promote antibiotic resistance. Keim's study provides a powerful example, says Ross Fitzgerald of the University of Edinburgh, UK.
Earlier this year the US Food and Drug Administration announced new restrictions on using preventive antibiotics in livestock, but the rules cover a small subset of drugs constituting just 0.2 per cent of antibiotics used on farms. As a result they are not expected to do much good.
Journal reference: mBio, in press
The Health Ministry’s Preventive Health Department has asked all local authorities to set up steering boards for epidemic prevention and control to combat Hand, Foot and Mouth disease and H5N1 avian flu that have spread rapidly and killed 11 children so far.
A child with HFMD being treated at the Obstetrics-Pediatrics Center in central Da Nang City on February 22, 2012, Photo: Tuoi Tre
At yesterday’s meeting on epidemic control, Nguyen Van Binh, head of the department, said local authorities should not wait to set up an interdisciplinary board until 24 hours after the declaration of epidemic as currently regulated, since such a delay will affect the efficiency of the fight against the diseases, he said.
The Health Ministry yesterday sent messages to chairpersons of the People’s Committees of provinces and cities asking them to prepare enough manpower, supplies and finances to cope with the epidemics.
Members of the local steering boards must be assigned to specific tasks to prevent and control the epidemic effectively.
The boards should advise all families to ensure hygienic conditions for children’s eating, drinking and playing. It is necessary to keep children’s toys clean and practice regular hand washing among children and their caretakers, the Health Minister said in the messages.
Veterinary workers in Quang Tri Province prepare to burn ducks that have contraced the H5N1 flu virus (Photo: Tuoi Tre)
The department reported that 6,328 HFMD cases had occurred in 60 of the country’s 63 provinces and cities during the first 6 weeks of the year, killing 9 children, and that the ratio of death to total HFMD cases in the period was 0.14 percent, equal to that in 2011, the year with the worst-ever HFMD epidemic.
This year’s epidemic may be more severe than that of last year, since it has broken out sooner - in January-February instead of April or May as in 2011, the department warned.
Meanwhile, after 20 months with no cases of humans contracting the H5N1 flu virus, the disease has re-occurred and spread to 12 provinces and cities so far, affecting 2 people in southern Kien Giang and Soc Trang provinces. Both have died.
Bac Ninh province is the latest that has been affected by the disease, following 11 other localities, including Thanh Hoa, Quang Tri, Ha Nam, Ha Tinh, Quang Nam, Hai Duong, Hai Phong, Thai Nguyen, Bac Giang, Soc Trang and Kien Giang, the Veterinary Department reported.
Vien Quang Mai, vice rector of Nha Trang city-based Pasteur Institute, states that the HFMD cases have increased in all central provinces, especially in Khanh Hoa and Binh Dinh, and killed a people in Da Nang city.
Compared to the same period last year, the number of affected localities this year has increased by three, said Dang Van Ky, head of the department’s Epidemiology Division.
Ky forecast that the number of HFMD patients this year may be the same as last year (110,000 cases), but the death toll may be lower, since there is now a new treatment regimen for the disease.
Health workers spray antiseptic to prevent the spread of H5N1 flu virus (Photo: Tuoi Tre)
Flu vaccine not highly effective
Ky warned that the H5N1 avian flu has evolved to have sub-clade 2.3.2, which itself developed into two types A and B, in which the former is three times more dangerous than the latter. Meanwhile, the H5N1-Re 5 vaccine, which has been used to vaccinate poultry in the country for the past several years, has been found too weak to cope with the sub-clade.
In addition, a survey of 30 provinces and cities showed that the average proportion of poultry bearing the H5N1 virus was 4.13 percent, with Ha Tinh taking the lead with 18 percent. These rates were far higher than those of last year, when the average rate was just 1.6-2 percent and the highest was not more than 6 percent.
The Ministry of Agriculture and Rural Development, which has asked the Finance Ministry to facilitate the import of 50 million doses of H5N1-Re 5, has therefore forecast that the country might suffer a large bird flu epidemic this year.
Ky also warned that in the past four years, the rate of mortality among H5N1 flu cases was 100 percent, while in the previous period, the rate was just 50 percent. This situation proves the virus has evolved to be more dangerous.