January 23, 2013
In light of their findings, Ghazi Kayali of St Jude Children's Research
Hospital in Memphis in the US and colleagues there and at Egypt's
National Research Center in Giza recommend that the H5N1 prevention and
control strategy in Egypt be updated and reinforced. Special
consideration should be given to the vaccination strategy, they say, and
the use of vaccines based on currently circulating viruses is
The group studied the cross-reactivity of six commercially available H5
poultry vaccines against recent H5N1 Egyptian isolates in a field
setting in Egypt. Only one vaccine based on an Egyptian H5N1 virus
induced high cross-reactive antibody titres.
The scientists suggest their results may be explained by the fact that
the seed viruses in these vaccines are genetically distinct from H5N1
viruses currently circulating in Egypt.
Full article: http://www.thepoultrysite.com/poultrynews/27711/study-reveals-reduced-efficacy-of-h5n1-vaccines-in-egypt