Vietnam-To isolate the direct contact with patients with influenza A/H5N1 #BIRDFLU #H5N1

To isolate the direct contact with patients with influenza A/H5N1

Antiseptic spray poison pens prevent diseases from spreading. Artwork. (Source: Internet)(VOV) - People who have contact with patients were also included in the watch list, if fever is found to be primary care to guide the next step.
25/2, Binh Duong Province Health Department confirmed detect a positive case of influenza A/H5N1. That patient Phu Truong Son, 22, born in Hoang Hoa district, Thanh Hoa province, staying in town 8, Phu Loi, Thu Dau Mot town.
Even in the afternoon 25/2, Pacific Health Department directs the Center for Preventive Medicine in collaboration with provincial Ho Chi Minh City Pasteur Institute in disease testing and Vu Cao Polyclinic Hospital where the Corps has treated four patients Truong Phu Son to take measures to isolate and take blood tests to monitor the direct contact with patients.The health sector also oversees local home Hau Tran Dinh, in the 12, eight quarters, Phu Loi, Thu Dau Mot - Place the patient in and apply measures to isolate those exposed to patients.Today (26/2) the work of disinfection, sterilization around where patients in the health sector development. Dr. Truong Ngoc Mai, station chiefs Health Phu Loi, Thu Dau Mot town, Binh Duong Province, said: "To this day, has the total of all household hygiene and surroundings where the patient temporarily residence. Tomorrow (17/2) will spray disinfection. People who have contact with patients were also included in the watch list, if found it to fever clinics for instructions on next steps. In the case of A/H5N1 flu, health centers have to monitor and track cases, monitor all those around it. "Earlier, after returning home for Tet Binh Duong and return to work for 3 weeks, on 17/2, Phu Truong Son high fever, difficulty breathing and was taken to hospital Vu Cao (Di An Town ) examination and treatment. However, the patient did not reduce hospital should be moved to 4 th Corps continued treatment. To 24/2, after moving to HCMC Hospital for Tropical Diseases, through testing, the samples of patients Phu Truong Son found positive for influenza A/H5N1.

http://vov.vn/Home/Cach-ly-nguoi-tiep-xuc-truc-tiep-voi-benh-nhan-mac-cum-AH5N1/20122/201316.vov

Vietnam-A/H5N1 flu patient still critical #H5N1 #BIRDFLU

A/H5N1 flu patient still critical(VNA) - With respect to influenza A/H5N1, from the beginning of this year the country has recorded two deaths.
As previously reported, the way 26/2, patients infected with influenza A/H5N1 in Binh Duong is still in critical condition.
Doctor, doctor Nguyen Van Vinh Chau, director of HCM City Tropical Hospital, said after 9 days of illness and medical treatment in hospitals Vu Cao, Di An Town, 4th Army hospital in Binh Ocean, but the health situation of the patient Truong Phu Son, 22, born in Hoang Hoa district, Thanh Hoa province, staying at 8th street, Phu Loi, Thu Dau Mot town, Binh Duong Province has events for the worse. Up to 24/2 patients were transferred to hospital treatment in tropical HCMC and to date 25/2 test results showed that patients infected with influenza AH5N1. Time, patients continue to be treated aggressively in the recovery room of the hospital in an emergency situation a poor prognosis, high fever, respiratory distress.According to doctors, Dr. Nguyen Van Vinh Chau: "The patient is not worse, but still not much improved compared with at admission. Avian influenza is a very high mortality rate. We are trying to treat and complete the engineering and testing, monitoring patient compliance with daily regimens of the Ministry of Health guidelines.
When moving up from lower levels, we have strict isolation of patients, full implementation of biosecurity measures for workers exposed to patients. In case some health workers have close contact with patients, we administered prophylactic. " Upon detecting A/H5N1 flu cases in Binh Duong, height 25/2 leader Ho Chi Minh City Pasteur Institute and Pacific Health Department held a meeting to prevent this disease and to quickly deploy sanitation, poison sterile environment where patients staying at the 12, eight quarters, Phu Loi, Thu Dau Mot town, Binh Duong Province.
Those who had contact with patients recently also been isolated health monitoring. To actively support Pacific prevention of disease, Pasteur Institute of Ho Chi Minh City just for the health sector in Binh Duong province taminflu 300 members. Identify the source of the disease on to prevent synchronous solutions, Representative HCMC Pasteur Institute offers three hypotheses about sources of infection: One is in Thanh Hoa Province, for the country during Tet, patients with eating duck several times, while Thanh Hoa is the provincial bird flu;
 second in Binh Duong where patients staying in third place at Cu Chi for patients participating in the slaughter and eat ducks Buy at Cu Chi.  http://www.baomoi.com/Home/SucKhoe/vov.vn/Benh-nhan-nhiem-cum-AH5N1-van-nguy-kich/7953364.epi

Bird flu spreads in Vietnam ominous #H5N1 #BIRDFLU

 2012-02-21
  The bird flu continues to spread in Vietnam that the prime minister yesterday 20/2 to a public emergency epidemic prevention and suppression services.

  AFP

  H5N1 influenza vaccine in poultry.

 In that situation should have self-protection measures, preventive as well as the community itself like?.

  Gia Minh noted the advice from experts and updated some information regarding the current avian influenza in Vietnam.

  Not have any specific drug treatment for influenza 

  Information from Vietnam Veterinary Department said earlier this week until February 20 H5N1 avian influenza has appeared in 11 provinces and cities nationwide. Đó là các địa phương Thanh Hóa, Quảng Trị, Sóc Trăng, Hà Nam, Hải Dương, Thái Nguyên, Kiên GIang, Bắc Giang, Hà Tĩnh, Hải Phòng và Quảng Nam. It is the local Thanh Hoa, Quang Tri, Soc Trang, Ha Nam, Hai Duong, Thai Nguyen, Kien Giang, Bac Giang, Ha Tinh and Hai Phong and Quang Nam.

There are places like Ho Chi Minh City said it was determined not to spread disease harmful to birds and humans as two cases of H5N1 virus died in Kien Giang and Soc Trang in last January.

  First of avian influenza situation and developments related diseases for as complex as this, some industry experts have given to all measures taken to prevent infection.

So far we certainly do not have any specific drug treatment for the flu at all.  On the mass media and some analysts say is Taniflu cure; but I only answer questions such relatively inaccurate.  Because there is no specific treatment should always occur in influenza

  medical Nguyen Dinh Nguyen

  Health authorities are checking cattle. AFP 

  MD Nguyen Dinh Nguyen from Australia talks about the measures to be applied in man:

. The prevention of influenza A H5N1 influenza prevention in particular and in general the characteristic inability to treat the flu: so far we certainly do not have any specific drug treatment for the flu at all.  On the mass media and some analysts say is Taniflu cure; but I only answer questions such relatively inaccurate.  Because there is no specific treatment method in which the flu should also occur. 
. The second point is also the year that vaccination against influenza that still has the flu.  The reason for the influenza A virus vaccine in flux that is applied to the production this year from two years ago, would have been expected, that fact may not occur as expected, desired.  In any flu also occurred, and heavy or light depending on the virus cycle back, and climatic conditions, environmental, human conditions which caused it to impact change, we are not far could know.

  What year also vaccinated against influenza, but still the flu.  The reason for the influenza A virus vaccine in flux that is applied to the production this year from two years ago, would have been expected, that fact may not occur as expected, desired.... 

Gà bệnh được mang đi thiêu hủy. Was taken sick chickens destroyed. AFP 

...From day 14 to February 16, the Department of Animal Health and representatives of international organizations in Vietnam such as the World Health WHO, the Food and Agriculture FAO, OIE World Animal Health conducted the workshop entitled 'Link four sides in the fight against bird flu '.

  Until last February 18, the National Steering Committee Prevention of avian influenza emergency meeting to discuss countermeasures. One of the measures was made to MARD for the prime minister to send written request for 13 billion to buy 50 million doses of H5N1 vaccine, strain Re-5 1st vaccination this year.

  According to forecasts made in 2012 it will need 327 million doses of vaccine to vaccinate poultry.  The immediate import of 50 million doses of vaccine from China to vaccinate poultry in the southern region where the H5N1 virus has not changed. 
  Information from the Vietnam Department of Animal Health said earlier Vietnam H5N1 virus detected three branches: one in the south branch, north branch and the branch 2.3.4 7 capable of highly infectious.Recently discovered in the north branch new virus is 2.3.2, however this division into two groups and the vaccine is no longer effective with this branch... 
. http://translate.googleusercontent.com/translate_c?hl=en&ie=UTF8&prev=_t&rurl=translate.google.com&sl=vi&tl=en&u=http://www.rfa.org/vietnamese/in_depth/the%2520measur-again-contrc-bird-flu-02212012141109.html&usg=ALkJrhiHgf6X7lwyuheCMZlooCTJDdGbmg

Four People Infected With Bird Flu Suspected Gowa #H5N1 #BIRDFLU

Four People Infected With Bird Flu Suspected Gowa

Selasa, 10 Januari 2012 08:00:50 Tuesday, January 10, 2012 08:00:50 Gowa: Risnawati, Nurbaya, Arsil, and Wahid had to undergo a medical examination in isolation rooms Sudirohusodo Wahidin General Hospital, Makassar, South Sulawesi, on Monday (9 / 1). Keempat warga Desa Relemba, Kecamatan Tombolopao, Gowa, ini mengeluh sakit pada tenggorokan dan deman tinggi. The four villagers Relemba, Tombolopao District, Gowa, it complained of pain in the throat and high fever.  Moreover, three members of their families in one house reportedly died with similar complaints.   Took no chances, officials from South Sulawesi Provincial Health Office, direct refer them to the RSU Wahidin. Rumah sakit ini adalah rumah sakit rujukan penyakit flu burung dan mengisolasi mereka di ruang pusat infeksi. This hospital is a referral hospital of bird flu disease and isolate them in the center of infection. . Hospital officials have taken blood samples are then tested four patients for laboratory and get special handling during the treatment. Although the preliminary results of newly diagnosed acute inflammation of the throat, medics are still awaiting results of lab tests to ensure the illnesses suffered by the four residents. http://translate.googleusercontent.com/translate_c?hl=en&ie=UTF8&prev=_t&rurl=translate.google.com&sl=id&tl=en&twu=1&u=http://www.sasak.net/16051___empat-warga-gowa-diduga-terinfeksi-flu-burung.html&usg=ALkJrhjiu5-SBWKrJ4t6hQfKMNdvg89klg

4 suspected with bird flu,3 family members dead #H5N1 #BIRDFLU

Four People Infected With Bird Flu Suspected Gowa
10.01.2012 04:03

Artikel Terkait
Liputan6.com, Gowa: Risnawati, Nurbaya, Arsil, and Wahid had to undergo a medical examination in isolation rooms Sudirohusodo Wahidin General Hospital, Makassar, South Sulawesi, on Monday (9 / 1). The four villagers Relemba, Tombolopao District, Gowa, it complained of pain in the throat and high fever. Moreover, three members of their families in one house reportedly died with similar complaints.
Took no chances, officials from South Sulawesi Provincial Health Office, direct refer them to the RSU Wahidin. This hospital is a referral hospital of bird flu disease and isolate them in the center of infection.

Hospital officials have taken blood samples are then tested four patients for laboratory and get special handling during the treatment. Although the preliminary results of newly diagnosed acute inflammation of the throat, medics are still awaiting results of lab tests to ensure the illnesses suffered by the four residents http://kesehatan.liputan6.com/read/371474/empat-warga-gowa-diduga-terinfeksi-flu-burung

Mutations I117V and I117M and Oseltamivir Sensitivity of Pandemic (H1N1) 2009 Viruses

CDC Emerging Infectious Diseases Issue
Suggested citation for this article: Hurt AC, Leang SK, Speers DJ, Barr IG, Maurer-Stroh S. Mutations I117V and I117M and oseltamivir sensitivity of pandemic (H1N1) 2009 viruses. Emerg Infect Dis [serial on the Internet]. 2011 Dec [date cited].

The neuraminidase inhibitors (NAIs) oseltamivir and zanamivir have been widely used in many countries to treat infection with influenza A pandemic (H1N1) 2009 virus. Since the start of the pandemic, >27,000 strains have been tested for oseltamivir resistance, of which 383 (1.4%) have contained the H275Y neuraminidase (NA) mutation, the same mutation that was found in oseltamivir-resistant prepandemic seasonal subtype H1N1 viruses that emerged in 2007–08. Apart from the H275Y mutation, a small number of other NAI resistance mutations have been detected in the NA of pandemic (H1N1) 2009 viruses, such as S247N (1), I223V (2), and I223R (3). Another NA mutation, I117M, has also recently been associated with oseltamivir resistance in pandemic (H1N1) 2009 viruses (4,5). The I117M NA mutation was detected in a virus from South Korea that was isolated from a patient before oseltamivir treatment and then was detected, with the H275Y mutation, in the same patient after oseltamivir treatment, although the dual mutations were not conclusively shown in the same virus (4,5).

In both studies, neither the I117M variant nor the dual I117M + H275Y strain were specifically tested for oseltamivir resistance. Instead, the viruses were assumed to be resistant on the basis of previous studies that described a reduction in oseltamivir sensitivity in influenza A (H5N1) viruses because of an I117V amino acid substitution (6,7), rather than the I117M substitution detected in their studies.

Other studies have documented that different amino acid substitutions at key NA residues can cause considerably different effects on NAI susceptibility and that these mutations can have a variable effect in different NA backgrounds (8). Therefore, we tested the assumption that the I117M mutation confers oseltamivir resistance and investigate the role of the I117M and the I117V mutations with and without the H275Y mutation in pandemic (H1N1) 2009 viruses.

[click on link for pdf document]