Friday, March 19, 2010 10:24
If in 2009, Vietnam has five fifths cases and deaths from influenza A/H5N1 is just over two months of 2010, Vietnam has recorded more cases of influenza A/H5N1 in which two cases died.
Why are infections and death from influenza A/H5N1 Left up fast? Whether influenza A/H5N1 virus was variable, increasing pathogenic as well as transmission from person to person?
Associate Professor-Dr Nguyen Tran Hien, Director of Institute of Hygiene and Epidemiology central exchange around this issue. '
Evolution of influenza A/H5N1 virus strains circulating in Vietnam last time any changes do not, sir?
First to emphasize a point is variable antigenic and genetic characteristics of the basic strains of influenza.
The results of research cooperation between the Department of Animal Health Ministry of Agriculture and Rural Development and the Center for Preventive and control disease in the United States strains of influenza A/H5N1 virus in poultry in the period from 2001 -- 2007 showed, there were 9 genotypes of virus circulating in Vietnam in which four new genotypes detected in 2007 in Vietnam but appear not find elsewhere. This may be due to the exchange and rearrangement of genetic material between the new grouping into Vietnam in 2007 are grouped subheadings 2.3.4 and has a circulation earlier.
In addition, research findings of influenza A/H5N1 virus strains in the Institute of Hygiene and Epidemiology Central shows replacement influenza A/H5N1 virus subgroup 1 (before 2007) by grouped 2.3.4 ( from 2007 to present), and high similarity to viruses isolated from poultry in the same time.
Distribution of the 15 tips influenza A/H5N1 virus has calculated the variation quickly, containing the genes of viruses from different animals. However, the antigenic variation that we track so far is small changes, no evidence that it has changed the toxic forces as well as from person to person spread of the virus. Cases occurred in the sink and no play related to each other.
Cause patients in Vietnam fall into respiratory failure status quickly and easily lead to death there is little variation in the antigens of the influenza A/H5N1 virus is not, sir?
Since 2003, strains of flu virus circulating in Vietnam are the strains are highly pathogenic. As mentioned above, although the antigenic changes of influenza A/H5N1 virus, but changes are small and no evidence of increased pathogenic strains of influenza virus circulating in Vietnam in time.
Mortality due to avian influenza A/H5N1 in Vietnam as well as equivalents in other countries in the region. For example, in 2009, the death rate in China is 4 / 7, in Indonesia and Vietnam 19/21 is 5 / 5.
Through analysis of recent fatal cases in Vietnam showed that most of the cases were hospitalized and treated Tamiflu late. Therefore, the diagnosis, detection and early treatment is important.
Backup is the best way we must regularly monitor closely the variations of the virus, while enhancing the implementation of preventive measures and positive initiative to limit the spread of avian influenza viruses from that limit the exchange of integration between the sub-group virus in poultry through vaccination campaigns for poultry vaccines, quarantine, restrict movement of poultry in and between the region and the successful implementation biosecurity measures in animal husbandry (such as quarantine, disinfection, target poisoning, hygiene cages ...).
Sir, influenza A/H5N1 virus strains in Vietnam are different from other countries are not in circulation disease?
Associate Professor-Dr Nguyen Tran Hien: As announced recently by the World Health Organization (WHO), in the period from January 9/2009-2/2010, H5N1 virus has changed little about the di Communication and antigens. H5N1 virus continued discovered in Africa, Asia and eastern China.
Countries report human cases is Cambodia, Egypt, Indonesia and Vietnam. Based on the analysis of the antigenic and genetic, influenza A/H5N1 virus was divided into four subgroups following: Grouping the virus was first detected in Cambodia, February 2 subgroups in Nepal, sub-group in Egypt 2.2.1 Update, subheadings 2.3.2 discovered in Hong Kong, Russia, Vietnam and Nepal, and subheadings 2.3.4 was discovered in Vietnam.
The results of this research is based on research results of Vietnam. Based on information about epidemiology and antigens of influenza A/H5N1 virus present in birds, due to the variations are small and not significant, WHO has also proposed a new H5N1 virus strains for research products H5N1 vaccine production room.
He has received about the progress of influenza A/H5N1 in 2010? Institute of Hygiene and Epidemiology Central will do to detect changes of the influenza A/H5N1 virus?
Associate Professor-Dr Nguyen Tran Hien: The research results of the Institute of Animal Health, Animal Health Department shows the circulation of the H5N1 virus in poultry, the proportion of healthy poultry carrying the virus is relatively high , especially in aquatic birds. Occurred while operating movement of poultry trade across borders and between regions. That explains why sometimes translated Left outbreaks in poultry and cases occur in people stroll play.
Forecast in 2010, if we ignore the subjective and the implementation of preventive measures positively and actively, then translated in poultry and the appearance of the sink has human cases continue to occur out. So people need to regularly apply the measures against bird flu but the Ministry of Health has recommended.
Next time, the Institute of Hygiene and Epidemiology Central will continue to work with the Center for Preventive and control disease in the United States conducted research as research feedback characteristics epidemiological study of influenza A/H5N1 cases in Vietnam, 2003-2010; research evidence about disease risk factors and questions influenza A/H5N1 virus infection in humans; study of the interaction and evolution of influenza A virus infection in humans and animals in Vietnam, including the virus highly pathogenic avian influenza A/H5N1.
- Thank you!.
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