Saturday, February 8, 2014

Experts: #H7N9 vaccine trial will take six years research to enable emergency

2014-02-09
Unfortunately, experts said, H7N9 avian influenza DNA vaccine to complete clinical evaluation in accordance with national legislation, officially put into use need to wait at least six years, but experts also pointed out that if the trend spread from person to person, or other special circumstances arise, the vaccine can be completed a Phase I clinical Emergency put into use after the test.

Shanghai Public Health Clinical Center, Shanghai Institute of Emerging Infectious Diseases reproduce the 7th news release, H7N9 avian influenza DNA vaccine has completed initial development in Shanghai, many Shanghai residents, hoping to be vaccinated as soon as possible. In this regard, experts said sorry, H7N9 avian influenza DNA vaccine to complete clinical evaluation in accordance with national legislation, officially put into use need to wait at least six years, but experts also pointed out that if the trend spread from person to person, or other special circumstances arise, the vaccine can be completed Phase I clinical trials after an emergency put into use. [ Ta Kung Pao reporter Xia Micro 28 (Xinhua) - Shanghai 
-snip-
It is understood, Shanghai ongoing H7N9 avian influenza antibodies developed in vitro testing is nearing completion, is expected to be finalized next month, the fastest antibody screening.
 
Previously, Wu Fan, director of Shanghai Municipal Center for Disease Control had explained during the breeding or selling poultry workers suffering from H7N9 avian flu rarely the reason that "many subtypes of avian influenza virus, the presence of cross-protection between subtypes, that if a person infected with a constant contact subtypes, immune machine experience, this immunity not only against infected subtype, while the body may have the ability to resist the avian influenza H7N9 virus. "cross-protection is a phenomenon in the same secondary antibody was also observed in study.
 
H7N9 antibodies against other viruses
According 徐建青 introduced, found in the patients infected with the H7N9 virus, the immune system will produce antibodies, "we have got 53 antibody clone", it is noted that "In these antibodies, we found that some antibodies against not only H7, also anti-H5, H3, etc. We call this antibody called broadly neutralizing antibodies. "
-snip
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