Vietnam-Concern over bird flu virus mutate to infect humans #BIRDFLU #H5N1

  08/02/2012 10:55

  Alteration of H5N1 virus in poultry in the absence of vaccine against the disease is an increased risk of virus mutate to spread from person to person.
  Afternoon 7-2, National Steering Committee for human avian influenza prevention have been meeting to deal with A/H5N1 flu situation occur again.  Dr. Tran Thanh Duong, deputy director of the Department of Preventive Health (MOH), said the notice of the World Health Organization: From early 2012 until now, the world recorded six cases of influenza A / H5N1, including 5 deaths in Cambodia, China, Egypt, Indonesia and Vietnam.
  In Vietnam, two cases and deaths from influenza A/H5N1 virus is a 18-year-old youth employed in Kien Giang duck and women 26 years in Soc Trang 36 weeks pregnant, previously exposed in infected birds.
  According to Yang, in the course of active treatment, women assigned caesarean section. Daughters of women weighing 2.3 kg, was born before the mother died a day and also was diagnosed with pneumonia caused by amniotic infection / suspected influenza A/H5N1, mechanical ventilation. After care and aggressive treatment at General Hospital Bac Lieu province, the child health is recovering well.
  Evaluation of two deaths from influenza A/H5N1, Dr. Nguyen Trong Khoa, deputy director of medical management (MOH), after nearly two years fears for Vietnam, no cases of influenza A / H5N1 can be neglected people.  Both deaths were said on the diagnosis and specific treatment when influenza was in advanced stages, rapid changes should lead to death.
  Dr Nguyen Van Kinh, Director of the Hospital for Tropical Diseases countries, to detect cancers that after 3-4 days suspected A/H5N1 flu patients making difficult treatment with good results.  Therefore, the medical establishment to continuously update the diagnosis and treatment of influenza.

  Prof. Dr. Nguyen Tran Hien, Director of the Institute of Hygiene and Epidemiology, said: Origin of flu cases is derived from poultry.  However, it is worth noting that the virus in poultry has been the transformation. NT-Rural Development Ministry has found the virus 2.3.2 branch into 2 groups.
 With older groups, injected flu vaccine for poultry only meet 75%, while the new group, the vaccine is not effective, so the risk of spread in poultry and humans is very large.  In addition, tests conducted on aquatic birds are breeding herds, sold in many places but no active disease but still carry the H5N1 virus.  "The conversion of H5N1 virus in poultry in the absence of vaccine against the disease is an increased risk of virus mutate to spread from person to person" - Mr. Show concern.
  The World Health Organization continue to warn the ability to combine the H1N1 and H5N1 influenza pandemic in humans is very high, thus requiring close supervision on both poultry and humans.  Deputy Minister of Health Nguyen Thanh Long also encouraged people absolutely do not slaughter sick birds, do not eat duck, undercooked poultry meat.

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Indo: Study on Oseltamivir [Tamiflu] Resistance after Death of 5 yo in Jakarta #H5N1 #Birdflu

January 27, 2012

This study against the backdrop of the alleged drug Oseltamivir resistance after the death of a child aged five years at Friendship Hospital due to bird flu infected.

Ministry of Health is conducting a study to examine whether or not there has been resistance to oseltamivir, which has been a mainstay of Indonesia in handling bird flu patients.

"It takes time indeed. To meguji resistance needed a tool that was very expensive, but we hope this year can be known means," said the head of Research and Development of the Ministry of Health, Trihono, in Jakarta, today.

Upon completion of the study will get what is concrete evidence of oseltamivir resistance has occurred.

Previously alleged drug Oseltamivir resistance after the death of a child aged five years in the Friendship Hospital due to bird flu infected.

From the first day of fever, the child had been given oseltamivir. But his condition continued to decline rapidly until she died.

Yet according to the Director General of Disease Control and Environmental Health Kemenkes, Tjandra Yoga Aditama, patients who were given oseltamivir within 48 hours of the first since the symptoms of bird flu emerged, the chances for recovery are very large.

Trihono said that drug resistance could be due to the previous dose given was too small.

"Can we overcome by the addition of dose or combination with other drugs," he said.

Trihono said, if oseltamivir resistance does occur, its impact can be very troublesome because Indonesia is very dependent on the type of drug.

Currently Indonesia has 1.4 million doses of Oseltamivir are partly derived from other state grants.

"We're really praying and hoping, not to the resistance that we worry about it come true, because it means we have to change all the drug-related policies," he said.

Indonesia-1.4 Million Drug Oseltamivir-Anticipation of Return Prepared outbreak of Bird Flu Cases #H5N1 #BIRDFLU

Wednesday, 25 January 2012JAKARTA-The Ministry of Health (Kemenkes) continues to anticipate the spread of H5N1 virus (bird flu), as the emergence of suspected bird flu cases in some areas.
Finally, the alleged cases of suspected bird flu hit the initials Ro, residents Mekarsari, Panongan, Tangerang regency. Health Minister (Menkes) Endang Rahayu Sedyaningsih said there are more than 1.4 million drug oseltamivir in anticipation of avian flu. "We are still adequate stock of drugs.
There are still 1.4 million drug oseltamivir in our warehouse. The amount of the drug in all 33 provinces. So this year we are still sufficient stock of drugs, expected to remain fairly even until next year, "he said in an interview with reporters at Kemenkes Office, Jakarta, yesterday. In addition, Endang expressed anticipation that other conducted by continued development of technology that is more sensitive to diagnose bird flu.
About technology for the diagnosis of bird flu, in fact it's been quite adequate....

 However, he explained that science will continue to grow. For its part the current bird flu diagnosed through examination of the throat and nose with a method Polymirasea Chain Reaction (PCR). PCR examination of this, he added, was done by conventional means and there is a real time.
He was able to deliver if the laboratory, followed by identification of the virus through sequencing (massage) to see gengen and protein-protein from the virus. So far, Endang mention for the diagnosis is done now has 100% accuracy. "But the diagnosis was time dependent. That is, depending on the period. There are already infected three months, but has not been detected. So there is need for a sufficient amount of virus, so it can be detected.
If only one, it would be difficult to detect the virus, "he explained. Director General of Disease Control and Environmental Health (P2PL) Kemenkes Tjandra YogaAditama explained, samples from patients suspected of bird flu has always been examined in the laboratory of Research and Development Health Kemenkes to know whether any bird flu virus or not.
Tjandra said, if you later have no results and the results and it was positive for bird flu, the results will be posted on the page Kemenkes. In addition it will be reported to the World Health Organization (WHO) / ​​- The World Health Organization as part of the International Health Regulations (IHR).

Meanwhile, the patient suspect bird flu, Ro, until yesterday was still critical.
Parties Tangerang District Hospital just stating the patient's condition is still critical, as when he entered four days ago to the government-run hospital. Head of Public Relations Achmad Muchlis Tangerang District Hospital explained, since entering last Saturday until now, Ro still on a ventilator, and an IV. "He's still critical," katanya.
Menurut Muchlis, Ro handled a team of doctors, who are experts in their fields such as pulmonary specialists, internal medicine, pathology, and anesthetics. 
http://www.seputar-indonesia.com/edisicetak/content/view/463475/

#h5n1 Bhutan-Possible suspects on Tamiflu #H5N1

Bird Flu: More surveillance underway

Saturday, January 14, 2012

(Bird flu update) Following the outbreak of bird flu in Changedaphu, popularly known as Kala Bazaar, medicines are being distributed to the people who came in contact with the dead poultry birds and their products. More surveillance is being conducted within three kilometre radius of the area.
Over 90 people have come in contact with the dead birds.
The officials from health and livestock have given health education and have disinfected the place.
The coops were being dismantled and sprayed with disinfectant. It was then burned to prevent the bird flu from spreading. The people, those who have consumed the dead and sick birds are being given Tami flu, the only drug available to treat this flu.
The Technical Focal Person for Avian influenza, Dr. Gosar Pemba, said that they took the samples from those people who were showing some signs of the disease. He added that it is too early to say as it could be normal flu, cough, sneezing and fever. “From these people we are taking samples and take it in our laboratory and see if any one of them has infection.”
Rapid test have shown negative results.
Meanwhile, more than 140 birds have been culled, 190 eggs destroyed belonging to 48 poultry owners.
This is the first case of bird flu outbreak recorded in the capital. Specialists suspect the recent outbreak in Tshimasham to be the source of the outbreak.
The culling process lasted at least four hours. According to the Bhutan Agriculture and Food Regulatory Authority’s (BAFRA) specialist J.B Gurung, the culling operation was carried out late night as the affected area is within the city and it could pose a high risk for human health.
The Director General of the Department of Livestock, Tenzin Dendhup, says 38 birds have died. Another eleven birds are sick.
According to BAFRA’s Director General disinfection of vehicles and strict monitoring of imports of poultry and poultry products by BAFRA at various entry points will resume.  http://www.bbs.com.bt/bbs/?p=8318

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