Unknown virus primer 1 child died of acute encephalitis
【╱ United Daily News reporter Zhou Guozhen, Zhan Jian-Fu, LIU Hui-min / Tainan - Taipei connection reported】
2009.01.23 02:53 am
Chi Mei Medical Center last weekend after another four were treated like a minor cold small children, four patients in one day the rapid deterioration, which郭姓girls died and one is still critically ill ICU. Chi Mei ruled out influenza and intestinal virus, suspected to be of unknown virus caused "acute encephalitis," has been informed and take samples sent to CDC.
It is understood that the four children from Tainan City, the new business and Yongkang city, on Friday and Saturday to the hospital. Because there is no fever patients with severe symptoms, that is, within 24 hours in a coma, and one person was killed and the hospital attached great importance to the "influenza virus PCR test", rule out the possibility of influenza virus; the other children did not enterovirus infection of the typical symptoms of oral ulcers , so as to find a result of the deadly bowel disease is extremely low.
The hospital said that at present, children can identify the brain, liver, heart and hematopoietic function of the virus were violated, the cause of death was encephalitis.
But many viruses may attack the brain, what kind of virus in the end, it is difficult to infer from the symptoms; have been taken, such as cerebral spinal fluid samples sent to CDC survey, the fastest but also the result of two weeks only.
郭姓children died on the 16th minor respiratory symptoms such as cough, parents to look at patient clinics, because there is no fever, doctors at first think it is generally cold, the boy was a minor abdominal pain, vomiting, drips soon unconscious, the doctor suspected virus possible violations of the nervous system, immediately transferred to Chi Mei Medical Center, the hospital has been in a coma.
郭姓girl died two days later by the rescue, and other similar course of three young children, they have gradually recovered, one person is still pediatric intensive care unit, unconscious index only three.
Chi Mei child neurologist Dr. Lai said明琪, causing rapid death郭姓students what kind of virus, but also to be tested; because there is no incidence of children with their families, casual-proliferation should not be a preliminary judge.
Department of Health says it has not received notification to the Chi Mei Hospital to check and found no cluster of cases, please do not panic people.
Chang Gung Children's Hospital, director of infection Huang Yu-cheng pointed out that clinical half pathogenic viral encephalitis can not find, at a time of peak season for influenza, the influenza viruses will be violations of the brain, parents should take extra care. Disease Control Department of Health Deputy Secretary for Jih-Haw Chou said that the occasional occurrence of sporadic cases of encephalitis, is not necessarily trigger a micro-organism or virus can not be too fast conclusion.
National Taiwan University Hospital, director of pediatric infection Li-Min Huang said that the hospital has also recently admitted to an acute encephalitis, the children had been in a coma.
He said that every year in November to March the following year is epidemic cerebrospinal meningitis epidemic period, but the case has been initially ruled out meningococcus trouble, after spinal puncture to obtain cerebrospinal fluid for virus culture, but can not find traces of the virus .
2009/01/23 United Daily News】
UNDIAGNOSED DEATH - TAIWAN: ENCEPHALITIS SUSPECTED, REQUEST FOR INFORMATION
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International Society for Infectious Diseases
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[1]
Date: January 23, 2008
Source: Huaxia [trans. by submitter, edited]
<http://huaxia.com/xw/twxw/2009/01/1300542.html>
4 Primary Students Infected by Unknown Virus in Tainan Area.
1 Dies, 1 in Grave Condition
----------------------------
Taiwanese media reports that 4 primary students with symptoms of mild
cold deteriorated within one day after seeking treatment. They are
suspected to be infected with an unknown pathogen. One has died.
Reports say that the 4 sick children 1st had mild colds, but sharply
deteriorated within one day. Among them one girl could not be saved
and another child is in grave condition. The hospital has ruled out
influenza and gastrointestinal pathogens. Acute encephalitis caused
by an unknown pathogen is suspected. The remains of the deceased have
been sent to Taiwan CDC for analysis.
The hospital stated that the patient's brain, liver, heart and
hematopoietic function were affected by the pathogen. Encephalitis
was determined to be the cause of death. But exactly what pathogen
caused this illness will not be announced for at least 2 weeks.
Vice Director of Taiwan CDC, Zhou Zhihao, said that these are isolated
cases and whether they are caused by a microorganism or pathogen
cannot be quickly determined.
--
Communicated by:
ProMED-mail Rapporteur Dan Silver
******
[2]
Date: 24 Jan 2009
Source: News PC Home, Taiwan [machine translated, edited]
<http://news.pchome.com.tw/living/tvbs/20090124/index-12327286183349939009.html>
9-year-old child died of suspected acute encephalitis
-----------------------------------------------------
In the Tainan region [of the country] a 9-year-old girl presented with
cough and symptoms of abdominal discomfort, influenza was suspected
and she was sent to the clinics for treatment. In the span of one
week she was comatose; at the same time, there are other children
presenting with similar symptoms that were admitted to the ICU
[intensive care unit] for treatment. According to the Taiwan CDC,
encephalitis is suspected, but confirmation of the etiologic agent is
still pending. Active surveillance in Tainan cities and counties
revealed one death and a 2nd serious case admitted to the ICU.
According to the CDC, the disease progresses rapidly, influenza virus
infection has been ruled out [by PCR according to another newswire
<http://www.udn.com/2009/1/23/NEWS/HEALTH/HEA1/4705049.shtml> -
Mod.MPP], as well as enterovirus infection. Jih-Haw Chou, the Deputy
Director of the CDC said: "the 9-year-old girl was admitted to the
hospital on 15 Jan 2009 with a complaint of abdominal discomfort, and
rapidly deteriorated."
The 9-year-old girl initially presented [at home] with a mild cough
and other respiratory discomfort symptoms; when abdominal discomfort
with vomiting began she was taken to a clinic and in less than 24
hours she was comatose, and was transferred to a large medical center
and died 2 days after admission to this larger medical center.
At present, the virus [presumed etiologic agent] has not been
identified, but patients demonstrate brain, liver, heart and
hematopoietic involvement. Specimens have been taken and results are
expected to take at least 2 weeks. According to Jih-Haw Chou: "the 2
cases were living in different regions and there is no [connection]
between them, so [we do not consider these 2 cases to be a common
cluster]".
--
Communicated by:
ProMED-mail
<promed@promedmail.org>
[According to the newswire reports on these cases, there seems to be a
presumed viral illness with multiorgan involvement (respiratory
presentation, gastrointestinal with hepatic involvement, cardiac
involvement and encephalitis), with laboratory tests ruling out
influenza and enteroviral etiologies. In addition, according to the
1st newswire, there have been 4 children presenting with this clinical
picture, including one who died. In the 2nd newswire there is mention
of 1 death and another in serious condition in an intensive care unit.
Without specific details on the types of the multiorgan disfunction
(such as type of hepatic and cardiac manifestations), it is difficult
to narrow down a differential diagnosis with any degree of confidence.
That being said, according to a recent report from the Taiwan CDC,
there were 7 cases of enterovirus 71 infection diagnosed in Taiwan in
December 2008 -- an unusual occurrence for that time of year (see
Enterovirus 71 - Taiwan 20090118.0223)
ProMED-mail would greatly appreciate receiving more information from
knowledgeable individuals in the region.
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