Sunday, January 25, 2009

Frequent passage of human avian influenza

[I don't know why this has a February 2, 2009 publication date.....at the very top of the page it says this: See article
Frequent passage of human avian influenza - the imminent danger of
2009-01-25 20:34]

"Financial" reporter Xu Chao Luo Changping张瑞丹

In this paper, see "Finance" magazine article 230 total

Publication Date: February 2, 2009


A short span of three days, Shinzo鲁湘China reported another three cases of human avian flu. Health Minister Chen Zhu, bluntly: "human avian influenza prevention and control work situation is extremely grim"

January 20, the provincial capital of Taiyuan in Shanxi Province is located in the outskirts of the Fourth People's Hospital (Taiyuan tuberculosis hospital) isolation zone ward B, only two of the highly pathogenic avian influenza (H5N1) in patients with early Peng (a pseudonym) , spent her fourth day of the hospital.

Although not yet out of danger period, but the early Peng overall situation has improved. That evening, she and B were the same in isolation can not meet the Grandpa HE Han-yong, and finally pass on the phone. "Grandpa, I want you." When HE Han-yong to hear him single-handedly brought up early Peng say, the tears could not help.

At this time, thousands of miles away in Changsha, Hunan, Mayor Shaxian Xingsha industrial zone, her father彭志文are also anxiously waiting for information from the Taiyuan.

For the ordinary middle-aged man, almost overnight, the whole family suffered a drowned: before January 7, because "severe pneumonia," he lost a five-month pregnant wife had Wen-mei; Today , he told of "financial" journalists, the biggest aspiration is the "daughter to keep." If the January 17 Peng was diagnosed early can finally out of danger, she will become China has so far confirmed 34 bird flu patients with celebrities, the first 11 lucky ones.

January 18, Shandong Provincial Health Department issued a circular saying, Jinan City, a 27-year-old woman was diagnosed with bird flu, and January 17, unfortunately, died; January 19, 16-year-old boy who Guizhou Wu Village in Huaihua City, Hunan Province People's Hospital was the first person diagnosed with bird flu, despite the rescue effort, but still on the morning of January 20 death of 8:10. Before January 5, the original in Beijing's Chaoyang District, Huang Yan-qing, 19-year-old girl, also died because of bird flu (see "Financial" in 2009 the first two "human bird flu再袭capital").

To enter in 2009, less than 20 days, China has confirmed four human cases of bird flu. The full-year 2008, China's only three bird flu.

January 20, the Chinese Ministry of Health held a special human avian influenza prevention and control of video and telephone conference, Health Minister Chen Zhu, in his speech bluntly: "human avian influenza prevention and control work situation is extremely grim."

Wen-mei's death


Drive east from the Changsha railway station about 20 kilometers, is part of the Xingsha Changsha Mayor Shaxian industrial zone. Hunan orange as automakers Chau Co., Ltd. Sales Manager of彭志文, there is a point of sale is located in the park.

The out-and-out for the man in Changsha, the disaster than it is too sudden. Prior to that, he is a room of a typical car the middle class. Apart from a small daughter early Peng, he also has a nine-year-old daughter. His wife, Wen-mei was also pregnant in the body, before the end of last year, and small daughter to live in Xiaoyi City, Shanxi Indus the home town of former Village. Until December 20, 2008 morning, she was only beginning to return to Changsha with Peng.

The next day, December 21 at noon, please彭志文cousin Wen-mei mother and daughter had dinner together, which could be considered接风and location of chickens and ducks in its operating business stars Town gray port before the farmers market stalls. 彭志文clearly remember that day at noon cousin has done a total of six dishes, including a complete free-range chicken. At that time, his wife and daughter were not involved in the preparation of meals, nor direct contact with poultry.

As the table only 56 meters from the booth, smell bad, some nausea and the Wen-mei did not eat too many things. Peng early as the favorite snacks, meals or eat more. However, they point the number of eating chicken.

December 29, 2008, Wen-mei told her husband, her appetite and some bad; the next day, but also that there is a fever during the day and at night coughing symptoms. December 31,彭志文Xingsha with his wife arrived at the Second District, a private clinic.

In this clinic, He lost a total of three bottles of liquid, until the day of New Year's Day in 2009. But tell彭志文"financial" journalists, the effect of transfusion is not good, the wife from the second floor of the home continues, legs and feet feel powerless, "and even some signs of collapse."

The clinic, a doctor told of "financial" journalists, Wen-mei was temporarily fever, but the third day of the disease has yet to see a fundamental turn for the better. Taking into account her pregnant, January 2, the clinic recommends that compared to professional women and children in Changsha County, Children's Hospital. January 4,彭志文adopted the proposal, with his wife went to Changsha County Children's Hospital for treatment of women and children. 彭志文recalled that in the hospitals, doctors have neither the lungs of the Wen-mei for inspection, has not requested to make films, but continued infusion. January 5 afternoon, Wen Mei hospital official. However, due to a serious condition, January 6 at 1 pm, Changsha County, women and children should be the requirements of Children's Hospital, Wen-mei was quickly transferred to hospital, one of the best Changsha Xiangya Hospital.

At this time of Wen-mei, was still conscious mind can not only get out of bed to walk, even its own toilet. But after, his condition has deteriorated rapidly; at 12:59 on January 7, Wen-mei's death.

Xiangya Hospital issued a death certificate said: severe pneumonia, ARDS, the medical examination showed the urgency of pulmonary syndrome.

At 11:00 on January 9, in the death of less than two days after the Wen-Mei's body was cremated, no autopsy. The death of a funeral parlor above description is "pneumonia deaths."

Misfortunes never come singly

彭志文did not expect, for this family, the nightmare is far from over.

Back in the early morning of January 7, Peng began early symptoms of fever. But at that time his wife's condition has been very serious, not too彭志文on the heart, only in a nearby pharmacy to buy a point just antipyretics. In Wen-mei after the death of January 11, Peng Yong He Hangen early and Grandpa and grandma together and return to the former Village of Shanxi Xiaoyi.

Peng early Hammerich uncle told "financial" journalists, the same day at noon to return to the former Village, this two-year-old girl developed greatly. January 13, Peng beginning of the clinic in the village infusion.

By January 14, Peng's condition continued to deteriorate in early. In the afternoon, she was sent to Xiaoyi City People's Hospital. After the film was shot, the hospital recommended for immediate transfer Fenyang Hospital. Because in a serious condition, the hospital also suggested Fenyang Peng directly to early to Taiyuan. January 14 at 6 pm, Peng formally transferred to the beginning of Children's Hospital in Taiyuan City. Had just settled his wife's funeral彭志文, receives a telephone call after the plane that night also hurried to Taiyuan. At 11:00 on January 15, Shanxi Province after the emergency group of experts in the consultation that can not be ruled out early Peng possibility of bird flu, they reported to the Ministry of Health.

彭志文recalled that Taiyuan, Shanxi杏花岭区CDC Changsha area had sent a fax early Peng finds suspected bird flu patients, and called for the early detection of close contact with the Peng-off for all.

January 17, in the early Peng was transferred to the Fourth People's Hospital in Taiyuan City, and was publicly confirmed human bird flu in the day,彭志文also returned to Changsha. At this point, he suddenly realized that, in view of his daughter and his wife's symptoms are so similar to his wife, Wen-mei is very likely did not die of severe pneumonia, and also died of bird flu.

Hong Kong University School of Medicine Department of Microbiology, Professor Guan Yi of the "financial", said that from the mother's symptoms, as well as the incidence of mother and daughter time to read, do not rule out the mother to the possibility of his daughter.

Unfortunately, Wen-mei has not been any case of anatomy cremation. Hunan Provincial Center for Disease Control and Prevention speaking on condition of anonymity, told the doctor of "financial" journalists, for the Wen-mei also died because of bird flu, "can only become a '无头案', and ultimately is likely to end up with nothing definite."

January 20 afternoon, women and children in Changsha County, Children's Hospital, out-patient and office are unwilling to accept the "financial" an interview with reporters and said that things on the Wen-mei knowledge.

Xiangya Hospital in the office, on duty in charge of "financial" reporters that Xiangya Hospital is the first time to deal with suspected human avian influenza case was diagnosed as pneumonia, "we consider ourselves the best."

After several days of rescue, especially in the injection of Beijing Kexing provided with a bird flu vaccine volunteers serum Since then, the beginning of the illness has been stabilized, the hope of survivors begin to be felt.

Shandong first anatipestifer

In槐荫District of Jinan City, who lives in Garden District of Zhu Wei Rong-xiang (a pseudonym) appears, she's wife, Zhang Xue (a pseudonym), Shandong Province, the first person who was diagnosed with bird flu patients, in the final days of life in the history is full of difficult to explain in words of the twists and turns and a sense of helplessness.

But no matter how the process, tragic outcome has already been cast: his dissatisfaction with two-year-old daughter, on January 17 Forever lost 27-year-old mother. Before that, both are plagued by the problem of unemployment. But relying on the district at a distance of 34 miles a night market麻辣烫do business, but also the maintenance of the entire family life. Zhu told the "Financial" reporters, a day in order to do business, they are purchasing from farmers market七里铺ball and vegetables, including duck blood.

January 5, Zhang began to loss of appetite, insomnia, but also accompanied by fever. Three days later, January 8, because of a bad headache, she accompanied her husband to the distance from the nearest residential community hospital. However, two days after the infusion, and Wen-mei, Peng early as Zhang's body temperature has not dropped. Zhu Jinan City with his wife came to the Fifth Hospital. After a blood test, Zhu was informed that in addition to low leukocyte content, no other problems, it is proposed to continue transfusion. By the next day (the 11th) morning and saw a high fever is still not to reclaim his wife, Zhu Wei once again made the decision to transfer. This is where the best local hospital - Shandong Provincial Hospital.

Lost fluid a day, his wife's condition still did not improve. January 12, Zhu Wei request to his wife to do chest film. Zhu Wei for "financial" reporter recalled that at the time of specialized outpatient clinics, doctors said that pneumonia, require hospitalization. Thus opened a number of drugs, and to continue transfusion.

After a few days, in the memory of Zhu Wei is gray: As Bedspace tension, has been unable to illness of his wife may have had in the emergency clinic, wheelchairs and even wooden planks around the bed; until at 15:00 on January 15, was able to transferred to Department of Respiratory Medicine, 33 beds.

By January 16, Zhu Wei found his wife not only did not retire a high fever, breathing has become increasingly difficult. In view of the hospital's delay in diagnosis was given, he put forward a formal application for transfer. After negotiations, Zhu Wei promised in the agreement signed by automatically discharged, and to settle all the costs under the premise of Zhang discharged. At 2:00 on January 17, Zhu and his wife finally sat through 120 links to the ambulance, set foot on the road to Beijing.

Zhu Wei for "financial", said that in accordance with the plan, he wants his wife to the Beijing Union Medical College Hospital, 301 hospitals or Chaoyang Hospital. At that time, he has realized that perhaps this is the last chance.

However, when the ambulance arrived and two hours drive from Beijing, Hebei Baoding, a sudden termination of the Zhu Wei phone all the plans: Zhang has been confirmed suffering from highly pathogenic avian influenza, we must return to Jinan. And in his carry-on Shandong Provincial Hospital issued diagnostic results, but also surprised to read, "ruled out SARS, and avian flu" message.

After the return of Jinan, Zhang was sent to Jinan City Hospital for Infectious Diseases. Despite rescue efforts, but it was too late. The day of 18:40, she eventually died.

"Financial" journalists have sought to interview multi-Shandong Provincial Hospital, as well as infectious disease hospital in Jinan, have been declined.

"Short-board" still worrying

January 19, the Chinese National Influenza Center director舒跃龙said in Beijing, from the current situation, China this year have occurred since the bird flu were found in different provinces, showing a high degree of dissemination of the situation. However, as found in patients with H5N1 virus, has not occurred with the human influenza virus re-allocation, that is not available in the interpersonal transmission capacity, there is no possibility of large-scale outbreak.

However, these cases left to disseminate experience and lessons should arouse enough attention.

In the past few years, China has moved from hardware to the system, the establishment of a set can be called a complete response, including human avian influenza outbreak, including sudden system. However, several have taken place in the actual response to the epidemic process, between reality and the ideal is still a large gap.

As early as in 2005, Hunan Xiangtan County 12-year-old girl He Yin's death, he was suspected human avian influenza may be a result. Unfortunately, there were no specimens left, was no solution into a "legal case" (see "Financial" 2005 22 "Hunan epidemic: He Yin's death").

Hunan Provincial Department of Health, a deputy department officials to accept the "financial" When interviewed by a reporter said that at present, the province has asked all medical institutions, according to Ministry of Health, the new version of "human bird flu treatment program" to deploy, but the Hunan village and township and county levels , including even some of the top three provincial hospitals, the diagnosis and treatment of avian flu is still to be improved. Most hospitals in terms of capacity or consciousness, are also there is an obvious gap. He admitted: "early discovery, early reporting, early quarantine, early treatment measures and emergency programs, there are still not in place." This situation not only in Hunan, in fact, are universal in the country.

The foregoing in Hunan Province Center for Disease Control and Prevention who declined to be named the "Financial" press frankly, the current control system in actual operation there are still a big problem, especially at the local reaction often "relatively conservative." It is said that the bird flu came to light after a deputy governor of Hunan Province also specially reminded, "It is the year, stability overrides everything else, we must pay attention to the impact." After all, once the epidemic open, often caused not a small place reality shock. To China's largest poultry farms and exporter in Shandong Province as an example, because of sudden epidemic, from January 17 onwards, Jinan, the largest local farmers market - above shop farmer's market, more than a dozen shops engaged in fresh chickens and ducks have been forced to close.

For this reason, "financial" press notes, both in Shanxi, Shandong and Hunan, the local government for the people the news of bird flu have handled quite a low profile. Only a short period of communications, the public has no way of knowing the reasons for patients with specific diseases, but also do not know how to draw in a targeted manner and draw lessons from them.

"Stealth" poultry outbreak

Equally of concern is still a few people in this avian flu incident behind its source of infection in poultry epidemic has always been without a trace to be found.

Changsha County Health Bureau, a person in charge of "financial," said the Chinese Ministry of Agriculture, Hunan Agriculture Department, Changsha City and Changsha County, four departments of the gray port farmers markets to monitor the epidemic investigation and concluded that: From 2008 Since December, no abnormal poultry deaths.

Subsequently, the above-mentioned departments in Changsha City of the three largest poultry wholesale markets and farm households, and even extended to Changsha, the three major source of the wholesale market - 45 townships, 42 farms have not found that poultry diseases.

Jinan in Shandong and the surrounding, it was "financial" reporter has learned that the same is not found in poultry in the epidemic. In fact, keeping accounts for one-sixth of China's export volume accounting for almost half the country's Shandong, there has never been previously H5N1 poultry outbreaks were reported.

However, the constant outbreaks of bird flu that China's animal epidemic situation has not completely disappeared compulsory immunization, but became more "hidden technology." After all, China has found bird flu cases were also the source of all poultry, that is, who can be traced back to the H5N1 poultry virus.

China in recent years in poultry in bird flu introduced compulsory vaccination policy for the control of poultry outbreaks have played an important role, but the stealth poultry epidemic potential clinical health threat may be even greater. Carrying a large number of clinical health H5N1 poultry virus, and its cross-regional flow more difficult to monitor; and frequent large-scale circulation, making the virus may have been greater variability in space.

"Financial" journalists around the survey found that most of them involved in live poultry farmers market transactions, health conditions are very bad, and some have even located in a densely populated neighborhood, so the virus can easily find access to human beings "export."

China Disease Prevention and Control Center, an expert on the "financial" reporter said frankly that in poultry in the abuse of antibiotics, as well as the narrow space poultry farms, have to break the biological balance of the original, so that mankind has had to face additional risks.

"Now a lot of farms in each area of the lives of chickens and ducks less than 1 square meters; the distance so close, there is also an objective to accelerate the contagious virus, making a higher infectious pathogens." He warned.

Many experts in a "financial" interview with reporters that, in the current situation, the true from the source to contain the spread of the epidemic and the threat posed by it is still a long way to go. Top priority, in addition to further strengthen the poultry epidemic monitoring and assessment, to break down pipe "human avian influenza," the Ministry of Health and the possession of "animal bird flu," the Ministry of Agriculture of communication between the pipeline, but also the need for the development of the existing poultry industry model to carry out a thorough reflection. ■

Our staff reporter Li Hu Jun, Chen Zhong-de-sac to have contributed to this article

Source: http://magazine.caijing.com.cn/20090124/78367.shtml

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