Wednesday, April 10, 2013

Chinese Academy of Sciences start of human infection with the H7N9 avian influenza virus in scientific and technological research

A few days ago, the Chinese Academy of Sciences under the current of human infection with the H7N9 avian flu, the country needs based on epidemic prevention and control, start "of human infection with the H7N9 avian influenza virus scientific and technological research.   In recent years, in the face of new hair, sudden major infectious diseases brought a serious threat to our people's lives and health, and economic and social development, the Chinese Academy of Sciences continue to promote the research and deployment of related fields, give full play in the etiology, propagation law and drug development the basic research strengths, the 2003 SARS, avian flu, 2009 H1N1 influenza sudden epidemic prevention and control of infectious diseases played a important technology supporting role. Research on the origin of the SARS coronavirus to determine the natural reservoir of the SARS virus and found that wild migratory birds play an important role in the global spread of the H5N1 avian influenza virus, to resolve the high-resolution crystal structure of the avian influenza virus RNA polymerase PA subunit of influenza A H1N1 influenza virus hemagglutinin and neuraminidase structure of the influenza virus and epidemic prevention and control of important guiding significance.   Chinese Academy of Sciences of the start of people infected with the H7N9 avian influenza virus in scientific and technological research, based on epidemic prevention and control of national demand around the scientific evaluation of the epidemic prevention and control, organization of the Institute of Microbiology of the hospital, Wuhan Institute of Virology, Institut Pasteur of Shanghai, force of about ten units of the Institute of Biophysics, Beijing Institute of Genomics, Shanghai Institute of Materia Medica, Institute of Zoology, Kunming Institute of Zoology, Chinese University of Science and Technology, will be synergistic with clinical units and the Chinese Center for Disease Control and Prevention (CDC), cooperation, focusing on play genomic and biological information analysis and evolutionary genomic studies advantage to study the virus traceability; play a pathogenic interspecies dissemination of research foundation, around the H7N9 virus breakthrough hosts limit the core issues, study the mutation of the virus and the interaction with the host; play Infection and Immunity Research Foundation to study human pathogenic mechanisms of H7N9 virus infection, scientific assessment of the immune response; viral protein structure research base advantage, antiviral live for Drug Evaluation and accelerate the research and development of new antiviral drugs for influenza. Ultimately hope to provide a solid scientific and technological support for the prevention and control of human infection with the H7N9 avian flu.   Characteristics of rapid variability and long-term coexistence with the human influenza virus, influenza virus infection prevention and control will be a long-term task. To this end, the CAS will establish a long-term study of the working mechanism of the influenza prevention and control research institutes integration influenza operational mechanism, in the hospital's major infectious disease research network on the basis of the Joint Research Centre, the establishment of the School of influenza, a system to study the deployment of The working mechanism of long-term research, to strengthen collaboration with the national first-line prevention and control units, and strive to break the scientific bottleneck of the flu epidemic prevention and control, and make due contribution to the prevention and control system for the National Influenza Science. (Source: Chinese Academy of Sciences website 2013, April 9)

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